1,2-Diiodobenzene Chemical Properties

Melting point:

>300°C

Boiling point:

152 °C/15 mmHg (lit.)

Density 

2.524 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.718(lit.)

Flash point:

>230 °F

storage temp. 

2-8°C

form 

Liquid

Specific Gravity

2.524

color 

Clear yellow to brownish

Water Solubility 

Slightly miscible with water.

Sensitive 

Light Sensitive

BRN 

1855315

Dielectric constant

5.7000000000000002

InChI

1S/C6H4I2/c7-5-3-1-2-4-6(5)8/h1-4H

InChIKey

BBOLNFYSRZVALD-UHFFFAOYSA-N

SMILES

Ic1ccccc1I

CAS DataBase Reference

615-42-9(CAS DataBase Reference)

NIST Chemistry Reference

1,2-Diiodobenzene(615-42-9)

EPA Substance Registry System

Benzene, 1,2-diiodo- (615-42-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-41-37/38

Safety Statements 

26-37/39-24/25

WGK Germany 

3

TSCA 

TSCA listed

HazardClass 

IRRITANT

HS Code 

29039990

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Dam. 1
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:1,2-Diiodobenzene
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1,2-Diiodobenzene Usage And Synthesis

Chemical Properties

clear yellow to brownish liquid

Uses

1,2-Diiodobenzene is useful for Suzuki reaction. It is also used in the synthesis of purino[8,9-f] phenanthridines. Further, it acts as a precursor for the synthesis of active pharmaceutical ingredients intermediate.

General Description

Photolysis of 1,2-diiodobenzene in cyclohexane, furan, benzene and benzene containing tetraphenylcyclopentadienone has been studied.

Synthesis

1,2-Diiodobenzene can be prepared from o-iodotrimethylsilane by a one-step reaction with iodine monomer.
0.5 mmol of o-iodotrimethylsilane, 0.5 mmol of monomeric iodine, and 1 mmol of 1-chloromethyl-4-fluoro-1,4-diazabicyclo[2.2.2]octane bis(tetrafluoroborate) salt were weighed into a 25 mL round-bottomed flask, and magnet and 3 mL of acetonitrile were added and stirred for 30 min under room temperature conditions, and at the end of the reaction, acetonitrile solvent was spun off using a rotary evaporator and the residue was dissolved with 1 mL of Dichloromethane was used to dissolve the residue, and the residue was analytically purified by silica gel chromatography to obtain 1,2-diiodobenzene in 96% yield.

1,2-Diiodobenzene(615-42-9)Related Product Information

• o-Phenylenediamine
• 1-Bromo-4-iodobenzene
• o-Xylene
• Bis(2-ethylhexyl) phthalate
• 4-Iodoanisole
• Phthalic acid
• (Diacetoxyiodo)benzene
• 4-DIIODOBENZENE,P-DIIODOBENZENE,diiodobenzen
• 2,3,5-TRIIODOBENZOIC ACID SODIUM SALT
• 1,2,3,4-tetrafluoro-5,6-diiodobenzene
• TETRAIODOPHTHALIC ANHYDRIDE
• 3,4,5-Triiodobenzoic acid
• 3,4-Diiodobenzoic acid
• 2,3,5-Triiodobenzoic acid
• 2-BROMO-1,4-DIIODOBENZENE
• 1,3-DIIODOBENZENE,1,3-diiodo-benzen、1,3-diiodobenzene、m-Diiodobenzene、1,3-diiodo-benzene、1,3-Dijodbenzol,1,3-Diiodobenzene,98+%,M-DIIODOBENZENE
• Sodium levothyroxine
• 4-Hydroxy-3,5-diiodophenylacetic acid