2-Amino-4-methylpyrimidine Chemical Properties

Melting point:

158-160 °C(lit.)

Boiling point:

194.6°C (rough estimate)

Density 

1 g/cm³

refractive index 

1.5340 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Crystalline Powder

pka

pK1: 4.11(+1) (20°C)

color 

Off-white to light brown

BRN 

108506

CAS DataBase Reference

108-52-1(CAS DataBase Reference)

NIST Chemistry Reference

2-Amino-4-methylpyrimidine(108-52-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

UV6485000

Hazard Note 

Irritant

HS Code 

29335990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Amino-4-methylpyrimidine Usage And Synthesis

Chemical Properties

OFF-WHITE TO LIGHT BROWN CRYSTALLINE POWDER

Uses

2-Amino-4-methylpyrimidine is a compound involved in a study about carbonylation as a key reaction in anaerobic acetone activation by Desulfococcus biacutus. 2-Amino-4-methylpyrimidine is formed as the product of a reaction between acetoacetaldehyde and guanidine.

Definition

ChEBI: 2-Amino-4-methylpyrimidine is an aminopyrimidine.

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 3526, 1951 DOI: 10.1021/ja01151a529

Purification Methods

Crystallise the pyrimidine from H2O or EtOH and sublime it in a vacuum. The picrate crystallises from EtOH and has m 235-236o(dec). [Beilstein 24 H 84, 25 III/IV 2152.]

2-Amino-4-methylpyrimidine(108-52-1)Related Product Information

• Niflumic acid
• 2-AMINO-5-BROMO-4-HYDROXY-6-METHYLPYRIMIDINE
• Sulfamethazine
• 2-AMINO-4-CHLORO-6-PHENYLPYRIMIDINE
• Sulfamerazine
• Nalidixic acid sodium salt
• ETHYL 2-AMINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
• 2-Amino-4-chloro-6-methylpyrimidine
• 2-Amino-6-methylpyrimidine-4(1H)-one,2-Amino-6-methylpyrimidine-4(3H)-one
• 2-AMINO-5-CHLOROPYRIMIDINE-4-CARBOXYLIC ACID
• 2-AMINO-5,6-DIMETHYL-4-HYDROXYPYRIMIDINE
• 2-Amino-4,6-dimethylpyrimidine
• 2-AMINO-6-HYDROXY-PYRIMIDINE-4-CARBOXYLIC ACID
• Nalidixic acid
• 2-Aminonicotinic acid
• Amfonelic acid
• BUPIRIMATE
• 2(1H)-Oxo-4-amino-5-methylpyrimidine,2-Hydroxy-4-amino-5-methylpyrimidine