5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT Chemical Properties

storage temp. 

-20°C

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-40

Safety Statements 

22-36/37/39

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT Usage And Synthesis

Uses

5-Fluoro-2′-deoxyuridine 5′-monophosphate (FdUMP) is used extensively in studies on the activity and function of thymidylate synthase (TS).

Uses

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt has been used as an anti-mitotic agent and is used extensively in studies on the activity and function of thymidylate synthase (TS).

Uses

5-Fluoro-2’deoxyuridine 5’Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity.

Biochem/physiol Actions

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (FdUMP) is an DNA synthesis inhibitor. FdUMP along with RNA synthesis inhibitor 3′-C-ethinylcytidine induces cell death in cervical cancer cells at nanomolar concentrations.

5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT(103226-10-4)Related Product Information

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