5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT Chemical Properties

storage temp. 

-20°C

solubility 

water: 50 mg/mL, clear, colorless to faint yellow or tan

form 

solid

InChI

1S/C9H12FN2O8P.Na.H/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(20-7)3-19-21(16,17)18;;/h2,5-7,13H,1,3H2,(H,11,14,15)(H2,16,17,18);;

InChIKey

DGEOOGBABXVZPJ-UHFFFAOYSA-N

SMILES

[Na].OC1CC(OC1COP(O)(O)=O)N2C=C(F)C(=O)NC2=O

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-40

Safety Statements 

22-36/37/39

WGK Germany 

3

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Carc. 2

MSDS

• Language:English Provider:SigmaAldrich

5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT Usage And Synthesis

Uses

5-Fluoro-2′-deoxyuridine 5′-monophosphate (FdUMP) is used extensively in studies on the activity and function of thymidylate synthase (TS).

Uses

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt has been used as an anti-mitotic agent and is used extensively in studies on the activity and function of thymidylate synthase (TS).

Uses

5-Fluoro-2’deoxyuridine 5’Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity.

Biochem/physiol Actions

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (FdUMP) is an DNA synthesis inhibitor. FdUMP along with RNA synthesis inhibitor 3′-C-ethinylcytidine induces cell death in cervical cancer cells at nanomolar concentrations.

5-FLUORO-2'-DEOXYURIDINE 5'-MONOPHOSPHATE SODIUM SALT(103226-10-4)Related Product Information

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