Basic information Safety Supplier Related

7-(Diethylamino)coumarin-3-carboxylic acid

Basic information Safety Supplier Related

7-(Diethylamino)coumarin-3-carboxylic acid Basic information

Product Name:
7-(Diethylamino)coumarin-3-carboxylic acid
Synonyms:
  • DEAC ACID
  • RARECHEM AB KA K024
  • 7-(DIETHYLAMINO)COUMARIN-3-CARBOXYLIC AC ID, FOR FLUORESC.
  • 7-DIETHYLAMINOCOUMARIN-3-CARBOXYLIC ACID
  • 7-(DIETHYLAMINO)-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID
  • 7-(Diethylamino)-2-oxo-2H-chromene-3-carboxylic acid, 7-(Diethylamino)-2-oxo-2H-1-benzopyran-3-carboxylic acid
  • 7ACC 1
  • 7ACC1
CAS:
50995-74-9
MF:
C14H15NO4
MW:
261.27
Product Categories:
  • DetectionFluorescent Indicators and Probes
  • Fluorescent Labels
  • Fluorescent Probes, Labels, Particles and Stains
  • Functional Group Reactive Labels
  • Functional Group Reactive Labels for SpectroscopyFluorescent Probes, Labels, Particles and Stains
  • Lipophilic and Membrane Probes
  • Other Fluorescent Labels
  • Dialkylcarbocyanine and Styryl probesFluorescent Probes, Labels, Particles and Stains
  • Biochemicals and Reagents
Mol File:
50995-74-9.mol
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7-(Diethylamino)coumarin-3-carboxylic acid Chemical Properties

Melting point:
222-224 °C (dec.)(lit.)
Boiling point:
464.7±45.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMF: soluble
pka
-98.36 ± 0.20, most acidic, temperature: 25 °C; 6.06 ± 0.20, most basic(at 25℃)
form 
Solid
color 
Bright orange solid; Orange crystals; Orange crystalline solid; Orange laths; Orange powder; Orange solid
Appearance
Solid
λmax
409 nm (Buffer pH 9.0)
BRN 
6145963
Major Application
Epoxy resinsphotoluminescent devices;lithographic platematerials; oil-repellent copolymers/coatings;polymer matrices; silica nanoparticles for imaging,security, and sensing applications
Biological Applications
Detecting hydrogenperoxide; evaluating iron ions; cysteine cathepsinsinhibitors; β-glucosidase inhibitors; humanmonoamine oxidase inhibitors; N-Methyl-D-aspartatereceptors (NMDARs) inhibitors; phosphateassay; probing actomyosin mechanism;treatingcancer/antitumor activity,treating cognitive deficits orschizophrenia;as a substrate for measuring proteinkinase activity
InChI
InChI=1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)
InChIKey
WHCPTFFIERCDSB-UHFFFAOYSA-N
SMILES
C1(=O)OC2=CC(N(CC)CC)=CC=C2C=C1C(O)=O
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Safety Information

Hazard Codes 
Xi
Safety Statements 
22-24/25
WGK Germany 
3
8-10
Hazard Note 
Irritant
HS Code 
29322090

MSDS

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7-(Diethylamino)coumarin-3-carboxylic acid Usage And Synthesis

Description

7-(Diethylamino)coumarin-3-carboxylic acid is an amine-reactive, non-activated fluorescent probe for bioconjugation.

Uses

7-(Diethylamino)-coumarin-3-carboxylic acid is a reagent for the derivatisation of amines and proteins. It has also been used for labelling synthetic peptides for high-throughput detection.

Uses

7-(Diethylamino)coumarin-3-carboxylic acid is an amine-reactive fluorescent label used for protein conjugation.

Excitation / Emission Maximum

430-440 nm/470-480 nm

7-(Diethylamino)coumarin-3-carboxylic acidSupplier

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