(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Chemical Properties

Melting point:

153-154 °C (lit.)

storage temp. 

Store at room temperature

form 

Powder

color 

White to off-white

InChI

InChI=1S/C28H28OP.BrH/c1-5-14-25(15-6-1)24-29-22-13-23-30(26-16-7-2-8-17-26,27-18-9-3-10-19-27)28-20-11-4-12-21-28;/h1-12,14-21H,13,22-24H2;1H/q+1;/p-1

InChIKey

DWYCJWXMZGVGJV-UHFFFAOYSA-M

SMILES

[P+](CCCOCC1=CC=CC=C1)(C1=CC=CC=C1)(C1C=CC=CC=1)C1C=CC=CC=1.[Br-]

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2931599090

MSDS

• Language:English Provider:SigmaAldrich

(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Usage And Synthesis

Uses

Reactant for preparation of:

• Spirocyclohexadienones via Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation
• Inhibitors of heat shock protein (Hsp90) as antitumor agents
• Carpanone-like molecules via an oxidative coupling/Diels-Alder cycloaddition sequence

Uses

(3-Benzyloxypropyl)triphenylphosphonium Bromide is a reagent used in the preparation of antitumor and Her2 degradation activity of geldanamycin and radicicol macrocyclic chimeras.

reaction suitability

reaction type: C-C Bond Formation

(3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE(54314-85-1)Related Product Information

• (3-(BENZOYLOXY)PROPYL)TRIPHENYLPHOSPHONIUM BROMIDE
• (3-BENZYLOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE