8-CYCLOHEXADECANONE Chemical Properties

Melting point:

22 °C

Boiling point:

193 °C

Density 

0.863±0.06 g/cm3(Predicted)

vapor pressure 

0.029Pa at 25℃

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Oil to Low-Melting Solid

color 

Colourless to Off-White

Odor

at 10.00 % in dipropylene glycol. musk clean laundered cloth dry balsamic waxy animal floral tobacco

Odor Type

musk

Water Solubility 

1.09mg/L at 20℃

LogP

5.628 at 25℃

EPA Substance Registry System

8-Cyclohexadecen-1-one (3100-36-5)

Safety Information

Hazard Codes 

N

Risk Statements 

50/53

Safety Statements 

60-61

8-CYCLOHEXADECANONE Usage And Synthesis

Chemical Properties

8-CYCLOHEXADECANONE is a viscous, clear, colorless to slightly yellow liquid with an elegant, fine, erogenous musk odor with a unique, sweet, powdery nitro musk undertone and balsamic, tobacco-like shades.
Due to its excellent stability and long-lasting properties, it is recommended for nearly all perfumery applications, especially for fine fragrances, personal care, and fabric care perfumes.
(E/Z)-8-Cyclohexadecenone is manufactured by monoepoxidation of 1,9-cyclohexadecadiene and subsequent rearrangement of the epoxide to the ketone.The starting material, 1,9-cyclohexadecadiene, is obtained from two molecules of cyclooctene by a metathesis reaction.

Uses

Animusk is a fragrant macrocyclic ketone that have been shown to have antitumor and antiinvasive effects on human fibrosarcoma cell.

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 4541, 1968 DOI: 10.1021/jo01276a058

Flammability and Explosibility

Not classified

Trade name

Globanone® (Symrise)

8-CYCLOHEXADECANONE(3100-36-5)Related Product Information

• 8-CYCLOHEXADECANONE
• Z-9-TETRADECENAL
• CIS-9-HEXADECENAL, 95
• 8-PENTADECANONE