5-Methylsalicylic acid Chemical Properties

Melting point:

150-154 °C (lit.)

Boiling point:

234.6°C (rough estimate)

Density 

1.2143 (rough estimate)

refractive index 

1.4945 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

Powder

pka

pK1:4.08 (25°C)

color 

White to beige

Water Solubility 

21.9g/L(100 ºC)

Merck 

14,2582

BRN 

1909076

CAS DataBase Reference

89-56-5(CAS DataBase Reference)

NIST Chemistry Reference

5-Methylsalicylic acid(89-56-5)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-37/38-41-36/37/38

Safety Statements 

26-36/39-22-36

WGK Germany 

3

RTECS 

GP3920200

HS Code 

29182110

MSDS

• Language:English Provider:2-Hydroxy-5-methylbenzoic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

5-Methylsalicylic acid Usage And Synthesis

Chemical Properties

5-Methylsalicylic acid is a white to beige powder that is soluble in basic water and in polar organic solvents. At neutral pH, the acid exists as 5-methylsalicylate Its functional groups include a carboxylic acid and a phenol group. It is one of four isomers of methylsalicylic acid.

Uses

5-Methylsalicylic acid was used in generation of o-sulfate conjugates in situ and their analysis by ultra-performance liquid chromatography-time-of-flight mass spectrometry.

Uses

Toxicity is similar to salicylic acid. 5-Methylsalicylic acid is used in manufacturing of dyes.

Preparation

5-Methylsalicylic acid can be prepared by hydroxylation of 3-methylbenzoic acid.

General Description

5-Methylsalicylic acid exhibits a significant cross-reactivity during fluorescent polarization immunoassay for salicylates in serum.

Purification Methods

Crystallise the acid from H2O. [Beilstein 10 H 227, 10 II 134, 10 III 516, 10 IV 610.]

5-Methylsalicylic acid(89-56-5)Related Product Information

• 3,5-Dinitrosalicylic acid
• CHLOROPHOSPHONAZO III
• Folic acid
• 3-Hydroxybenzoic acid
• Acetylsalicylic acid
• Methyl salicylate
• 3-Nitrosalicylic acid
• 2,3,4-Trihydroxybenzoic acid
• 2'-Hydroxy-3-phenylpropiophenone
• Methylparaben
• 3,5-Dihydroxybenzoic acid
• 5-Nitrosalicylic acid
• Ethyl 2-(Chlorosulfonyl)acetate
• 4-Hydroxybenzoic acid
• Salicylic acid
• Glycine
• Butylparaben
• 4-METHYLSALICYLIC ACID,4-Methyl-2-hydroxybenzoic acid,p-methylsalicylic acid