PROPENTOFYLLINE Chemical Properties

Melting point:

64-66°C

Boiling point:

541.4±56.0 °C(Predicted)

Density 

1.25±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Store in freezer, under -20°C

solubility 

H2O: soluble12.4mg/mL

pka

0.58±0.70(Predicted)

form 

solid

color 

white

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

WGK Germany 

3

RTECS 

UO8438700

Toxicity

LD50 in male, female mice, male, female rats (mg/kg): 900, 780, 1150, 940 orally; 168, 170, 180, 195 i.v.; 375, 346, 199, 196 i.p.; 450, 508, 400, 338 s.c. (Inazu)

PROPENTOFYLLINE Usage And Synthesis

Description

Propentofylline is a nootropic indicated for cerebrovascular disorders. Other indications currently under investigation include senile dementia, stroke and hypoxia.

Chemical Properties

Off-White Solid

Originator

Hoechst AG (W.Germany)

Uses

A c-AMP phosphodiesterase inhibitor. A nerve growth factor stimulator. An adenosine transport inhibitor. A non-selective adenosine receptor antagonist. Nootropic.

Definition

ChEBI: Propentofylline is an oxopurine.

brand name

Hextol

Biochem/physiol Actions

c-AMP phosphodiesterase inhibitor; nerve growth factor stimulator; adenosine transport inhibitor; non-selective adenosine receptor antagonist.

PROPENTOFYLLINE(55242-55-2)Related Product Information

• Tiopronin
• Theophylline
• Propentofylline-d6
• 1-N-BUTYL-3,7-DIMETHYLXANTHINE
• Pentoxifylline
• 1-N-HEXYLTHEOBROMINE
• 3-Methyl-7-propylxanthine
• 3-ETHYL-3H-IMIDAZOLE-4-CARBALDEHYDE
• PROPENTOFYLLINE
• CAFFEINE
• 7-ETHYL THEOPHYLLINE
• 1-N-PROPYL-3,7-DIMETHYLXANTHINE