(+/-)-11-HYDROXY-DELTA9-THC
(+/-)-11-HYDROXY-DELTA9-THC Basic information
- Product Name:
- (+/-)-11-HYDROXY-DELTA9-THC
- Synonyms:
-
- 11-HYDROXY-DELTA(9)-TETRAHYDROCANNABINOL
- (+/-)-11-HYDROXY-DELTA9-THC
- RACEMIC DRONABINOL METABOLITE
- (6ar-trans)--pentyl
- 11-hydroxy-delta(sup9)tetrahydrocannabinol
- 6h-dibenzo(b,d)pyran-9-methanol,6a,7,8,10a-tetrahydro-6,6-dimethyl-1-hydroxy-3
- 7-hydroxy-delta(sup1)tetrahydrocannabinol
- 11-hydroxy-delta9-tetrahydro-*cannabinol--dea sch
- CAS:
- 36557-05-8
- MF:
- C21H30O3
- MW:
- 330.46
- Product Categories:
-
- Heterocycles
- Various Metabolites and Impurities
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 36557-05-8.mol
(+/-)-11-HYDROXY-DELTA9-THC Chemical Properties
- Melting point:
- 136-138°C
- Boiling point:
- 437.1±45.0 °C(Predicted)
- Density
- 1.071±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml - pka
- 9.78±0.60(Predicted)
(+/-)-11-HYDROXY-DELTA9-THC Usage And Synthesis
Chemical Properties
Off-White to Pale Yellow Solid
Uses
A metabolite of ?9-Tetrahydrocannabinol (?9-THC) (T293200).
Definition
ChEBI: A phytocannabinoid that is Delta9-tetrahydrocannabinol in which the methyl group at C-11 has been hydroxylated . Major metabolite of Delta9-tetrahydrocannabinol.
References
[1] BILLY R. MARTIN. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols[J]. Life sciences, 1981, 29 6: Pages 565-574. DOI: 10.1016/0024-3205(81)90434-3
[2] KATHARINA ELISABETH GRAFINGER Wolfgang W. Determination of the Cross-Reactivity of the Biological Metabolite (-)-trans-Δ9-Tetrahydrocannabinol-Carboxylic Acid-Glucuronide (THC-COOH-Gluc) for Cannabinoid Immunoassays.[J]. Journal of analytical toxicology, 2021, 45 3: 291-296. DOI: 10.1093/jat/bkaa063
[3] TINA M. BLAND . CYP2C-catalyzed delta(9)-tetrahydrocannabinol metabolism: Kinetics, pharmacogenetics and interaction with phenytoin[J]. Biochemical pharmacology, 2005, 70 7: Pages 1096-1103. DOI: 10.1016/j.bcp.2005.07.007
[4] REBECKA COLES. Simultaneous analysis of the Delta9-THC metabolites 11-nor-9-carboxy-Delta9-THC and 11-hydroxy-Delta9-THC in meconium by GC-MS.[J]. Journal of analytical toxicology, 2005, 29 6: 522-527. DOI: 10.1093/jat/29.6.522