2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Basic information
- Product Name:
- 2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid
- Synonyms:
-
- 2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid
- CLOMID
- CLOMIPHENE CITRATE SALT
- CLOMOXIR
- CLOMPHID
- PERGOTIME
- SEROPHENE
- 2-[4-(2-CHLORO-1,2-DIPHENYLETHENYL)-PHENOXY]-N,N-DIETHYLETHANAMINE CITRATE SALT
- CAS:
- 88431-47-4
- MF:
- C14H17ClO3
- MW:
- 268.74
- EINECS:
- 200-035-3
- Mol File:
- 88431-47-4.mol
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Chemical Properties
- Boiling point:
- 411.5±35.0 °C(Predicted)
- Density
- 1.251±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.66±0.20(Predicted)
Safety Information
- Hazard Codes
- T
- Risk Statements
- 60-63
- Safety Statements
- 53-36/37-45
- WGK Germany
- 3
- RTECS
- YE0875000
MSDS
- Language:English Provider:SigmaAldrich
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Usage And Synthesis
Uses
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
General Description
Clomiphene citrate, 2-[4(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine(Clomid), is used as an ovulation stimulant inwomen desiring pregnancy. Although early literature refersto clomiphene as an estrogen antagonist, it is more accuratelya SERM. Clomiphene is chemically a mixture of two geometricisomers, zuclomiphene, the cis-isomer, and enclomiphene,the trans-isomer. In animal studies, these isomershave different estrogenic actions in different tissues.Zuclomiphene appears to have weak agonist actions on alltissues studied, whereas enclomiphene has antagonist actionson uterine tissue, but agonist action on bone tissue. The actionsof clomiphene in humans are likely a composite of theactions of the two isomers.
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