DMT-dT Phosphoramidite
DMT-dT Phosphoramidite Basic information
- Product Name:
- DMT-dT Phosphoramidite
- Synonyms:
-
- 5'-O-DMT-thymidine 3'-CE phosphoramidite
- DMT-dT PhosphoraMidite
- 5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-thyMidine 3'-[2-cyanoethyl N,N-bis(1-Methylethyl)phosphoraMidite]
- 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
- 5'-O-DMT-2'-deoxythymidine-3'-CE Phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-cyanoethyl Phosphoramidite
- 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
- CAS:
- 98796-51-1
- MF:
- C40H49N4O8P
- MW:
- 744.81
- EINECS:
- 685-410-3
- Product Categories:
-
- Pharmaceutical
- RNAi
- DNA
- Amidite
- Mol File:
- 98796-51-1.mol
DMT-dT Phosphoramidite Chemical Properties
- Density
- 1.22 at 20℃
- vapor pressure
- 0-0Pa at 20-50℃
- storage temp.
- Sealed in dry,2-8°C
- solubility
- soluble, clear
- form
- powder or granules
- pka
- 9.55±0.10(Predicted)
- color
- white to off-white
- InChI
- InChI=1/C40H49N4O8P/c1-27(2)44(28(3)4)53(50-23-11-22-41)52-35-24-37(43-25-29(5)38(45)42-39(43)46)51-36(35)26-49-40(30-12-9-8-10-13-30,31-14-18-33(47-6)19-15-31)32-16-20-34(48-7)21-17-32/h8-10,12-21,25,27-28,35-37H,11,23-24,26H2,1-7H3,(H,42,45,46)/t35-,36+,37+,53?/s3
- InChIKey
- UNOTXUFIWPRZJX-DJKSPSSYNA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,38,r|
- LogP
- 5.8 at 20℃
DMT-dT Phosphoramidite Usage And Synthesis
Uses
5''-O-[Bis(4-Methoxyphenyl)phenylmethyl]-thymidine 3''-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a nucleotide and reactant used in the solid-phase synthesis of phosphorothioate oligonucleotides, and in the synthesis of lipophilic 5''-phosphoramidate derivatives of DNA and RNA oligonucleotides.
Chemical Properties
5'-O-DMT-Thymidine-CE Phosphoramidite is also known as DMT-dT Phosphoramidite. The IUPAC Name of this compound is (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It allows for the introduction of thymidine units into oligonucleotides. Also, it has been used in various applications, including the synthesis of natural and unnatural DNA and RNA strands.
DMT-dT PhosphoramiditeSupplier
- Tel
- 13326014885
- service@nugene.com.cn
- Tel
- 021-64757213
- info@hongene.com
- Tel
- 025-86506605 13952030024
- 13811988123@139.com
- Tel
- 17333066501
- shengwen.fang@huanaok.com.cn
- Tel
- 022-022-25327698 18920479040
- sales@cosychem.com
DMT-dT Phosphoramidite(98796-51-1)Related Product Information
- Phenyltriethoxysilane
- Diphenyldimethoxysilane
- 2,3-Dimethylbutane
- Thymidine
- Diisopropyl ether
- N,N-Diisopropylethylamine
- 4-Methoxyphenylacetone
- Trimethoxypropylsilane
- 3-Aminopropyltriethoxysilane
- p-(2-Methoxyethyl) phenol
- FLUORESCEIN-DT CEP
- 5-ETHYNYL-DU CEP
- NPOM-CAGED-DT CEP
- BBQ-650-DT CEP
- DABCYL-DT CEP
- 2'-O-METHYL-5-METHYL-U CEP
- 5'-O-FDMT-THYMIDINE CEP
- 5-METHOXYMETHYL-DU CEP