9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE
9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE Basic information
- Product Name:
- 9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE
- Synonyms:
-
- RIMCAZOLE DIHYDROCHLORIDE
- 9-(3-(3,5-dimethyl-l-piperazinyl)propyl)-,dihydrochloride,cis-9h-carbazol
- bw234u
- cis-9-(3-(3,5-dimethyl-1-piperazinyl)propyl)-9h-carbazoledihydrochloride
- 9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE
- Rimcazole2HCl
- Rimcazole
- 9-[3-(3,5-dimethyl-1-piperazinyl)propyl]carbazole dihydrochloride
- CAS:
- 75859-03-9
- MF:
- C21H29Cl2N3
- MW:
- 394.38
- Mol File:
- 75859-03-9.mol
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9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE Chemical Properties
- storage temp.
- Store at +4°C
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 10 mM in water
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9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE Usage And Synthesis
Uses
Rimcazole Dihydrochloride is a small molecule antagonist of the σ-1 receptor and inhibits tumor cell survival.
Biological Activity
Antagonist at σ receptors (IC 50 values are 1480 and 386 nM at σ 1 and σ 2 receptors respectively). Also binds to the dopamine transporter (IC 50 = 57.6 nM) and inhibits dopamine uptake. Reduces the stimulatory effects of cocaine in vivo .
storage
Store at +4°C
9-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDESupplier
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