3-Methoxybenzamide Chemical Properties

Melting point:

132.5-135.5 °C (lit.)

Boiling point:

280.0±23.0 °C(Predicted)

Density 

1.143±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml,Ethanol: 1 mg/ml

form 

A crystalline solid

pka

15.81±0.50(Predicted)

Water Solubility 

Soluble in water.

BRN 

2206857

InChI

InChI=1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10)

InChIKey

VKPLPDIMEREJJF-UHFFFAOYSA-N

SMILES

C(N)(=O)C1=CC=CC(OC)=C1

CAS DataBase Reference

5813-86-5(CAS DataBase Reference)

Safety Information

WGK Germany 

3

RTECS 

CV5463333

HS Code 

2924297099

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-Methoxybenzamide Usage And Synthesis

Uses

3-Methoxybenzamide is act as an inhibitor of ADP-ribosyltransferase. It is also a weak inhibitor of the essential bacterial cell division protein FtsZ. Alkyl derivatives of 3-Methoxybenzamide are potent antistaphylococcal compounds with suboptimal drug-like properties.

Biological Activity

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum).

in vitro

3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation. 3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants.

3-Methoxybenzamide(5813-86-5)Related Product Information

• 3,4-DIMETHOXYBENZHYDRAZIDE
• Actinomycin D
• 3,5-DIMETHOXY-4-HYDROXYBENZAMIDE
• 2,5-DIMETHOXYBENZHYDRAZIDE
• 3,4,5-TRIMETHOXYBENZHYDRAZIDE
• 3,4,5-TRIMETHOXYBENZAMIDE
• 3-Methoxybenzamide
• 3,5-DIMETHOXYBENZHYDRAZIDE
• 3-METHOXYBENZHYDRAZIDE
• 3,5-Dimethoxybenzamide
• 3-ETHOXYBENZAMIDE
• 3,5-DIMETHOXY-4-HYDROXYBENZHYDRAZIDE
• 3-ETHOXYBENZHYDRAZIDE
• 2,3-Difluoro-4-methoxyBenzamide
• Glibenclamide
• malic acid, compound with 4-amino-N-[1-(benzyl)piperidin-4-yl]-5-chloro-2-methoxybenzamide (1:1)
• Amisulpride
• 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide monohydrochloride