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Bromocresol green

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Bromocresol green Basic information

Product Name:
Bromocresol green
Synonyms:
  • Phenol,4,4’-(3H-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromo-3-methyl-,S,S-dioxide
  • tetrabromo-m-cresolphthaleinsulfone
  • vertdebromocresol
  • BACILLUS OF CALMETTE AND GUERIN
  • BCG
  • BROMCRESOL GREEN
  • BROMOCRESOL GREEN SULTONE FORM
  • BROMOCRESOL BLUE
CAS:
76-60-8
MF:
C21H14Br4O5S
MW:
698.01
EINECS:
200-972-8
Product Categories:
  • Sulfonephthalein
  • Flavones, Flavonoids, FoodstuffsDerivatization Reagents TLC
  • Organic Acids, Carboxylic AcidsDerivatization Reagents
  • Derivatization Reagents TLC
  • TLC Reagents, A-C
  • TLC ReagentsDerivatization Reagents TLC
  • Organics
  • Analytical Chemistry
  • Indicator (pH)
  • TLC Stains
  • B
  • Stains and Dyes
  • Stains&Dyes, A to
  • TLC Visualization Reagents (alphabetic sort)
  • pH Indicators
  • TLC Visualization Reagents (by application)
  • AR
  • 76-60-8
Mol File:
76-60-8.mol
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Bromocresol green Chemical Properties

Melting point:
225 °C (dec.) (lit.)
Density 
0.79 g/mL at 20 °C
Flash point:
12 °C
storage temp. 
no restrictions.
solubility 
Solubility Sparingly soluble in water; soluble in ethanol, ether, ethyl acetate
form 
Powder/Solid
pka
4.7(at 25℃)
Boiling point:
626.0±55.0 °C(Predicted)
color 
Pale orange
PH Range
3.8(YELLOW)-5.4(BLUE)
PH
3.8~5.4
Water Solubility 
slightly soluble
λmax
423nm, 444nm, 617nm
Merck 
14,1386
BRN 
372527
Stability:
Stable. Incompatible with strong oxidizing agents.
Major Application
Sol-gel matrix, fuel cells, sensors, display device, inks, paints, one-steptester for ammonia, cosmet-tester for ammonia, packaging system, textiles, cleansing products, detergents, cosmetics, diapers, identifying fresh and stale rice, monitoring fish spoilage, detecting carbohydrates, lacting acid bacteria, treating neoplasms, cancer, vaginal infection test method, drugs, dental materials
LogP
7.800 (est)
CAS DataBase Reference
76-60-8(CAS DataBase Reference)
EPA Substance Registry System
Bromcresol green (76-60-8)
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Safety Information

Hazard Codes 
F,Xi,Xn
Risk Statements 
11-36-67-36/37/38-20/21/22
Safety Statements 
7-16-24/25-26-37/39-36
RIDADR 
UN 1219 3/PG 2
WGK Germany 
3
RTECS 
SJ7456000
Autoignition Temperature
399 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29349990

MSDS

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Bromocresol green Usage And Synthesis

Chemical Properties

tan to yellow crystals

Uses

Bromocresol Green is a pH sensitive indicator used in the growth medium for microorganisms and titrations. It is useful in various colorimetric detection studies and as an actively tracking dye for DNA agarose gel electrophoresis. It acts as an inhibitor of prostaglandin E2 transport protein. It is also used in TLC for visualizing compounds containing functional groups having pKa less than 5.

Uses

Bromocresol Green (BCG) is a pH sensitive triphenylmethane dye useful in a variety of colorimetric detection technologies. BCG is used as a tracking dye for DNA agarose gel electrophoresis, in protein determinations and in charge-transfer complexation processes. In TLC BCG is used for visualisation of the compounds with functional groups whose pKa is below 5.0.

Uses

As indicator, pH 3.8 yellow; pH 5.4 blue-green.

Definition

ChEBI: Bromocresolgreen is a member of benzofurans.

Hazard

Moderately toxic.

Purification Methods

Crystallise the dye from glacial acetic acid or dissolve it in aqueous 5% NaHCO3 solution and precipitate it from the hot solution by dropwise addition of aqueous HCl. Repeat this until the UV/VIS-extinction did not increase 423nm. It is an indicator: at pH 3.81 at max (yellow) and pH 5.4 (blue-green). [Beilstein 19/3 V 460.]

Bromocresol green Preparation Products And Raw materials

Preparation Products

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