Sodium cinnamate
Sodium cinnamate Basic information
- Product Name:
- Sodium cinnamate
- Synonyms:
-
- 2-Propenoicacid,3-phenyl-,sodiumsalt
- 3-phenyl-2-propenoicacisodiumsalt
- CINNAMIC ACID SODIUM SALT
- CINNAMYLIC ACID SODIUM SALT
- 3-PHENYLACRYLIC ACID SODIUM SALT
- 3-PHENYLPROPENOIC ACID SODIUM SALT
- 3-BENZENEPROPENOIC ACID SODIUM SALT
- fortificar
- CAS:
- 538-42-1
- MF:
- C9H9NaO2
- MW:
- 172.16
- EINECS:
- 208-691-2
- Product Categories:
-
- Cinnamic acid
- FINE Chemical & INTERMEDIATES
- 11
- Mol File:
- 538-42-1.mol
Sodium cinnamate Chemical Properties
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C9H8O2.Na.H/c10-9(11)7-6-8-4-2-1-3-5-8;;/h1-7H,(H,10,11);;
- InChIKey
- QOTHILGGRBOKOP-UHFFFAOYSA-N
- SMILES
- C(C1C=CC=CC=1)=CC(=O)O.[NaH]
- CAS DataBase Reference
- 538-42-1(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Propenoic acid, 3-phenyl-, sodium salt (538-42-1)
Sodium cinnamate Usage And Synthesis
Chemical Properties
Sodium cinnamate is a white to light yellow solid at room temperature.It is used in the manufacture of cinnamyl chloride and anticoagulant.Important intermediate of ozagrel, benzyl cinnamate, benzyl chloride,cinnamamide.
Uses
Sodium cinnamate can be used to manufacture cinnamic acid, cinnamyl chloride, cinnamamide. At the same time, it is also suitable for improving the cooling system and automobile resistance pad of various engine mechanical equipment, which is beneficial to the long-distance use of automobiles.
Synthesis
The commonly used production method of sodium cinnamate is to react cinnamic acid with sodium carbonate aqueous solution, then concentrate and dry it.
in vivo
Cinnamic acid sodium (100 mg/kg; gavage) activates PPARα to protect the loss of dopaminergic neurons, restore striatal fibers and neurotransmitters, and improve the behavioral functions in MPTP-intoxicated mice[1].
| Animal Model: | 6-8 weeks, C57BL/6 mice (18 mg/kg MPTP-HCl, i.p.; at 2-h intervals for 4 times)[1] |
| Dosage: | 100 mg/kg |
| Administration: | Gavage; starting from 3 h after the last injection of MPTP |
| Result: | Protected nigral TH levels, protected striatal innervation and neurotransmitters, restored locomotor deficit, increased the activation of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in primary mouse astrocytes, protected striatal TH via PPARα. |
Sodium cinnamate Preparation Products And Raw materials
Preparation Products
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Sodium cinnamate(538-42-1)Related Product Information
- Sodium formate
- Diclofenac sodium
- Sodium bicarbonate
- Sodium gluconate
- Sodium percarbonate
- Cinnamic acid
- Sodium silicate
- Sodium acetate
- Sodium chlorite
- Sodium polyacrylate
- Trisodium phosphate
- Sodium alginate
- Sodium benzoate
- Sodium hydroxide
- Sodium citrate
- Sodium chloride
- Sodium carbonate
- Cinnamaldehyde