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TYRPHOSTIN A63

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TYRPHOSTIN A63 Basic information

Product Name:
TYRPHOSTIN A63
Synonyms:
  • [4-HYDROXYBENZYL]MALONONITRILE
  • AG 43
  • ALPHA-CYANO-(4-HYDROXY)DIHYDROCINNAMONITRILE
  • RARECHEM AL BY 0097
  • TYRPHOSTIN AG 43
  • TYRPHOSTIN A63
  • TYRPHOSTIN 63
  • TYRPHOSTIN A63 99%
CAS:
5553-97-9
MF:
C10H8N2O
MW:
172.18
Mol File:
5553-97-9.mol
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TYRPHOSTIN A63 Chemical Properties

storage temp. 
2-8°C
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Safety Information

WGK Germany 
3

MSDS

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TYRPHOSTIN A63 Usage And Synthesis

Uses

Tyrphostin 63 (compound 13) is an epidermal growth factor receptor (EGFR) inhibitor with IC50 and Ki values are 375 and 123 μM, respectively[1].

Definition

ChEBI: 2-[(4-hydroxyphenyl)methyl]propanedinitrile is a member of phenols.

References

[1] Gazit A, et al. Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J Med Chem. 1989 Oct;32(10):2344-52. DOI:10.1021/jm00130a020

TYRPHOSTIN A63Supplier

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