Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Organic Chemistry >  Hydrocarbons and derivatives >  Hydrocarbon halides >  6-Chloro-2-fluoropurine

6-Chloro-2-fluoropurine

Basic information Safety Supplier Related

6-Chloro-2-fluoropurine Basic information

Product Name:
6-Chloro-2-fluoropurine
Synonyms:
  • 6-CHLORO-2-FLUORO-9H-PURINE
  • 6-CHLORO-2-FLUOROPURINE
  • 6-CHLORO-2-FLUORPURINE
  • 2-fluoro-6-chloropurine
  • 6-Chloro-2-fluoro-7H-purine 98%
  • 6-CHLORO-2-FLUORO
  • 6-chloro-2-fluoro-7H-purine
  • 6-Chloro-2-fluoropurine >
CAS:
1651-29-2
MF:
C5H2ClFN4
MW:
172.55
EINECS:
634-083-5
Product Categories:
  • Heterocyclic Building Blocks
  • PurinesHeterocyclic Building Blocks
  • Biochemistry
  • Nucleobases and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Thiazoles
  • Halides
  • Purine
  • Purines
  • Fused Ring Systems
  • Building Blocks
  • Halogenated Heterocycles
Mol File:
1651-29-2.mol
More
Less

6-Chloro-2-fluoropurine Chemical Properties

Melting point:
162-163°C
Boiling point:
221.8±50.0 °C(Predicted)
Density 
1.98±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
pka
4.88±0.20(Predicted)
form 
powder to crystal
color 
White to Light yellow to Green
InChI
InChI=1S/C5H2ClFN4/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H,8,9,10,11)
InChIKey
UNRIYCIDCQDGQE-UHFFFAOYSA-N
SMILES
N1C2C(=NC(F)=NC=2Cl)NC=1
CAS DataBase Reference
1651-29-2(CAS DataBase Reference)
More
Less

Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22-37/39-26
Safety Statements 
26-36/37/39-39
WGK Germany 
3
HS Code 
29335990
More
Less

6-Chloro-2-fluoropurine Usage And Synthesis

Description

6-Chloro-2-fluoropurine is a heterocyclic building block. It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs) in vitro. 6-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV) in vitro.

Chemical Properties

Beige solid

Uses

6-Chloro-2-fluoropurine is used as a reagent in the synthesis of several organic compounds including that of 2''-Fluoro-3''-Hydroxymethyl-5''-deoxythreosyl phosphonic acid nucleoside analogues which may potentially act as antiviral agents. It is also used in the synthesis of 2'',5'',5''-trifluoro-3''-hydroxy-apiosyl nucleoside phosphonic acid analogues which may possess potent anti-HCMV properties.

6-Chloro-2-fluoropurineSupplier

Nanjing Meixu Industry Co., Ltd. Gold
Tel
0519-83730180 18015866816
Email
15732310@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
INTATRADE GmbH
Tel
+49 3493/605464
Email
sales@intatrade.de
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com