6-Chloro-2-fluoropurine Chemical Properties

Melting point:

162-163°C

Boiling point:

221.8±50.0 °C(Predicted)

Density 

1.98±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml

pka

4.88±0.20(Predicted)

form 

powder to crystal

color 

White to Light yellow to Green

CAS DataBase Reference

1651-29-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-41-37/38-22-37/39-26

Safety Statements 

26-36/37/39-39

WGK Germany 

3

HS Code 

29335990

6-Chloro-2-fluoropurine Usage And Synthesis

Description

6-Chloro-2-fluoropurine is a heterocyclic building block. It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs) in vitro. 6-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV) in vitro.

Chemical Properties

Beige solid

Uses

6-Chloro-2-fluoropurine is used as a reagent in the synthesis of several organic compounds including that of 2''-Fluoro-3''-Hydroxymethyl-5''-deoxythreosyl phosphonic acid nucleoside analogues which may potentially act as antiviral agents. It is also used in the synthesis of 2'',5'',5''-trifluoro-3''-hydroxy-apiosyl nucleoside phosphonic acid analogues which may possess potent anti-HCMV properties.

6-Chloro-2-fluoropurine(1651-29-2)Related Product Information

• 6-Chloropurine
• Cyhalothrin
• Purine
• Flucloxacillin sodium
• Fluroxypyr
• Cyhalothrin
• Flucloxacillin
• Fluorine
• Difluorochloromethane
• 2-Fluoropurine
• 2-FLUOROPYRIMIDINE
• 6-Chloro-2-fluoropurine