4-Methoxybenzenesulfonyl chloride Chemical Properties

Melting point:

39-42 °C(lit.)

Boiling point:

173 °C14 mm Hg(lit.)

Density 

1.3836 (estimate)

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

DMSO (Slightly)

form 

Crystalline Solid

color 

White to beige

Water Solubility 

decomposes

Sensitive 

Moisture Sensitive

BRN 

609005

Stability:

Moisture Sensitive

CAS DataBase Reference

98-68-0(CAS DataBase Reference)

NIST Chemistry Reference

P-methoxybenzenesulfonyl chloride(98-68-0)

Safety Information

Hazard Codes 

C

Risk Statements 

34-29

Safety Statements 

26-36/37/39-45-28A-27

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

10-21

Hazard Note 

Corrosive/Moisture Sensitive

HazardClass 

8

PackingGroup 

II

HS Code 

29093090

MSDS

• Language:English Provider:4-Methoxybenzene-1-sulfonyl chloride
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Methoxybenzenesulfonyl chloride Usage And Synthesis

Chemical Properties

white to beige crystalline solid

Uses

4-Methoxybenzenesulfonyl chloride is used as an anti-HIV as Pharmaceutical Intermediates. It also acts as protecting group agent for various nitrogen functions.

Application

4-Methoxybenzenesulfonyl chloride is a versatile sulfonating agent; useful for the preparation of sulfonamides or as an N-protecting group.

Synthesis Reference(s)

Synthesis, p. 852, 1986 DOI: 10.1055/s-1986-31803

Solubility in organics

4-Methoxybenzenesulfonyl chloride sol acetone, acetonitrile, EtOH, MeOH, dioxane, H2O.

storage

4-Methoxybenzenesulfonyl chloride is corrosive and a lachrymator. Store at room temperature under anhydrous conditions. Use in a fume hood.

4-Methoxybenzenesulfonyl chloride(98-68-0)Related Product Information

• 4-Nitrobenzenesulfonyl chloride
• Calcium chloride
• p-Anisaldehyde
• Sulfuryl chloride
• Ammonium chloride
• Mepiquat chloride
• Benzyl chloride
• Sodium chloride
• N-Acetylsulfanilyl chloride
• Polyvinyl chloride
• p-Anisidine
• 4-Chlorobenzenesulfonyl chloride
• Benzenesulfonyl chloride
• Choline chloride
• 4-Methoxybenzylchloride
• 4'-Methoxyacetophenone
• 4-Methoxybenzyl cyanide
• 4-Methoxyphenylacetic acid