N-CARBOBENZOXY-DL-LEUCINE Chemical Properties

Melting point:

54 °C

Boiling point:

442.8±38.0 °C(Predicted)

Density 

1.158±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)

form 

Solid

pka

4.00±0.21(Predicted)

color 

White to Off-White

BRN 

4695869

CAS DataBase Reference

3588-60-1(CAS DataBase Reference)

Safety Information

WGK Germany 

3

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich

N-CARBOBENZOXY-DL-LEUCINE Usage And Synthesis

Description

It is a biologically active amino acid usually used as nutritional supplements, flavour enhancer, and components for preparing pharmaceutical and biochemical products such as amino acid infusion and comprehensive amino acid, hypoglycemic agent, plant growth promoter. Specifically, it is found that ingestion of a high whey protein, leucine-enriched supplement resulted in a larger overall postprandial muscle protein synthesis rate in healthy older people compared with a conventional dairy product.¹ Moreover, this substance possesses the most marked anabolic characteristics in acting as a trigger element for the initiation of protein synthesis, thus guaranteeing the healthy human skeleton muscle metabolism.² In addition, this chemical may be involved in the promotion of plant growth.³

Reference

1. Luiking, Y. C.; Deutz, N. E. P.; Memelink, R. G.; Verlaan, S.; Wolfe, R. R., Postprandial muscle protein synthesis is higher after a high whey protein, leucine-enriched supplement than after a dairy-like product in healthy older people: a randomized controlled trial. Nutr. J. 2014, 13, 14.
2. Wilkinson, D. J.; Hossain, T.; Hill, D. S.; Phillips, B. E.; Crossland, H.; Williams, J.; Loughna, P.; Churchward-Venne, T. A.; Breen, L.; Phillips, S. M.; Etheridge, T.; Rathmacher, J. A.; Smith, K.; Szewczyk, N. J.; Atherton, P. J., Effects of leucine and its metabolite -hydroxy--methylbutyrate on human skeletal muscle protein metabolism. J. Physiol.-London 2013, 591, 2911-2923.
3. Glick, B. R.; Todorovic, B.; Czarny, J.; Cheng, Z. Y.; Duan, J.; McConkey, B., Promotion of plant growth by bacterial ACC deaminase. Crit. Rev. Plant Sci. 2007, 26, 227-242.

Chemical Properties

White powder

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