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5-HYDROXYMETHYLCYTOSINE

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5-HYDROXYMETHYLCYTOSINE Basic information

Product Name:
5-HYDROXYMETHYLCYTOSINE
Synonyms:
  • 4-AMINO-2-HYDROXY-5-HYDROXYMETHYLPYRIMIDINE
  • 5-(Hydroxymethyl)Cytosine Hydrochloride
  • 5-Hydroxymethylcytosinefreebase
  • 2(1H)-Pyrimidinone, 4-amino-5-(hydroxymethyl)- (9CI)
  • 4-AMINO-5-(HYDROXYMETHYL)PYRIMIDIN-2-OL
  • 4-Amino-5-(hydroxymethyl)pyrimidin-2-ol ,97%
  • 4-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone
  • 4-Amino-5-hydroxymethyl-2(1H)-pyrimidinone
CAS:
1123-95-1
MF:
C5H7N3O2
MW:
141.13
Product Categories:
  • Nucleic acids
  • PYRIMIDINE
  • Elisa Kit-Rat Elisa Kit
Mol File:
1123-95-1.mol
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5-HYDROXYMETHYLCYTOSINE Chemical Properties

Melting point:
>299.85°C
Boiling point:
258.15°C (rough estimate)
Density 
1.3818 (rough estimate)
refractive index 
1.6190 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Sparingly), Methanol (Slightly, Heated, Sonicated)
form 
Solid
pka
8.61±0.10(Predicted)
color 
Pale Yellow to Beige
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29335990

MSDS

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5-HYDROXYMETHYLCYTOSINE Usage And Synthesis

Chemical Properties

Grey solid

Uses

5-(Hydroxymethyl)cytosine is a DNA pyrimidine nitrogen base.It may regulate gene expression or prompt DNA demethylation. 5-Hydroxymethylcytosine may be especially important in the central nervous system, as it is found in very high levels there.

Definition

ChEBI: A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a hydroxymethyl group.

5-HYDROXYMETHYLCYTOSINESupplier

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