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FMOC-N(HMB)-GLY-OH

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FMOC-N(HMB)-GLY-OH Basic information

Product Name:
FMOC-N(HMB)-GLY-OH
Synonyms:
  • 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}[(2-hydroxy-4-methoxyphenyl)methyl]amino)acetic acid
  • N-Fmoc-N-(2-hydroxy-4-methoxybenzyl)glycine
  • N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-(2-hydroxy-4-methoxybenzyl)glycine
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-(2-HYDROXY-4-METHOXY-BENZYL)-GLYCINE
  • N-ALPHA-FMOC-N-ALPHA-(2-HYDROXY-4-METHOXYBENZYL)GLYCINE
  • FMOC-N(HMB)-GLY-OH
  • FMOC-(HMB)GLY-OH
  • Fmoc-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH
CAS:
148515-78-0
MF:
C25H23NO6
MW:
433.45
Mol File:
148515-78-0.mol
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FMOC-N(HMB)-GLY-OH Chemical Properties

Boiling point:
679.4±55.0 °C(Predicted)
Density 
1.338±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.81±0.10(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C25H23NO6/c1-31-17-11-10-16(23(27)12-17)13-26(14-24(28)29)25(30)32-15-22-20-8-4-2-6-18(20)19-7-3-5-9-21(19)22/h2-12,22,27H,13-15H2,1H3,(H,28,29)
InChIKey
SFNQJVQTVYXPFN-UHFFFAOYSA-N
SMILES
C(O)(=O)CN(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)CC1=CC=C(OC)C=C1O
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Safety Information

HazardClass 
IRRITANT
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FMOC-N(HMB)-GLY-OH Usage And Synthesis

Chemical Properties

White to off-white powder

Definition

Fmoc-N(HMB)-Gly-OH serves as a building block in the synthesis of peptides. The Fmoc group acts as a protective group, allowing for selective deprotection and subsequent coupling reactions during solid-phase peptide synthesis. Fmoc is often preferred over Boc because of its ease of cleavage.

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