2,3-Difluoropyridine Chemical Properties

Boiling point:

125-126°C

Density 

1.265 g/mL at 25 °C

refractive index 

n20/D 1.427

Flash point:

125-126°C

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

soluble in Chloroform, Methanol

form 

clear liquid

pka

-2.85±0.10(Predicted)

color 

Colorless to Light yellow

InChI

InChI=1S/C5H3F2N/c6-4-2-1-3-8-5(4)7/h1-3H

InChIKey

OGVLEPMNNPZAPS-UHFFFAOYSA-N

SMILES

C1(F)=NC=CC=C1F

CAS DataBase Reference

1513-66-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,F,Xi,N,Xn

Risk Statements 

10-36/37/38-50-41-22

Safety Statements 

26-36/37/39-36/37-61-45-25-16

RIDADR 

1993

WGK Germany 

2

Hazard Note 

Toxic

HazardClass 

3

PackingGroup 

III

HS Code 

29333990

2,3-Difluoropyridine Usage And Synthesis

Chemical Properties

Pale yellow liquid

Uses

2,3-Difluoropyridine is an intermediate used in the preparation of 2,7-diazaspiro[4.5]decan-1-one derivatives as 11-b hydroxysteroid dehydrogenase type 1 inhibitors and mineralocorticoid receptor antagonists.

2,3-Difluoropyridine(1513-66-2)Related Product Information

• 3-Aminopyridine
• 2,5-Dimethylpyridine
• Flupirtine
• 2,6-Lutidine
• 2,5-PYRIDINEDICARBOXYLIC ACID
• DIPIPERIDINOMETHANE
• 2,3-Difluoropyridine-4-boronic acid
• Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
• 3-Chloro-2,4,5,6-tetrafluoropyridine
• 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
• 2,3,5,6-Tetrafluoropyridine
• 2,5-DIFLUOROPYRIDINE
• 2,4-DIFLUORO-PYRIDINE
• Pentafluoropyridine
• 4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE
• 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE
• 2 3 5 6-TETRAFLUORO-4-METHYLPYRIDINE 9&
• 3,5-DIFLUOROPYRIDINE