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Dolutegravir 4-Desfluoro Impurity
Dolutegravir 4-Desfluoro Impurity Basic information
- Product Name:
- Dolutegravir 4-Desfluoro Impurity
- Synonyms:
-
- Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- 4-Defluoro Dolutegravir
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
- Dolutegravir Impurity C (4-Defluoro Dolutegravir)
- Doultegravir 2-F Impurity C
- Dolutegravir Impurity 46
- Dolutegravir Impurity 49
- CAS:
- 1863916-87-3
- MF:
- C20H20FN3O5
- MW:
- 401.39
- Mol File:
- 1863916-87-3.mol
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Dolutegravir 4-Desfluoro Impurity Chemical Properties
- Boiling point:
- 671.6±55.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- pka
- 4.50±1.00(Predicted)
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Dolutegravir 4-Desfluoro Impurity Usage And Synthesis
Uses
4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir 4-Desfluoro ImpuritySupplier
Beijing Comparison Pharmaceutical Technology Co., Ltd
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- 010-52878169 15701683040
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ChemStrong Scientific Co.,Ltd
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Shanghai Kewel Chemical Co., Ltd.
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Hubei Yangxin Medical Technology Co., Ltd.
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Shanghai CR Corporation Limited
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