4-(4-Aminophenyl)butyric acid Chemical Properties

Melting point:

121-124 °C (lit.) 121-133 °C

Boiling point:

363.7±17.0 °C(Predicted)

Density 

1.177±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

4.70±0.10(Predicted)

color 

Light Beige to Light Brown

InChI

InChI=1S/C10H13NO2/c11-9-6-4-8(5-7-9)2-1-3-10(12)13/h4-7H,1-3,11H2,(H,12,13)

InChIKey

RBHLFWNKEWLHBP-UHFFFAOYSA-N

SMILES

C1(CCCC(O)=O)=CC=C(N)C=C1

CAS DataBase Reference

15118-60-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

WGK Germany 

3

HS Code 

2922498590

MSDS

• Language:English Provider:SigmaAldrich

4-(4-Aminophenyl)butyric acid Usage And Synthesis

Description

4-(4-Aminophenyl)butyric acid (4-APB) is an important organic compound derived from butyric acid, which is used as a synthetic intermediate for pharmaceuticals or the synthesis of various compounds. It is also used in drug mechanism studies and is thought to be an agonist for certain G-protein coupled receptors and may also interact with other proteins in the signal transduction pathway. In addition, 4-(4-aminophenyl)butyric acid has been found to inhibit monoamine oxidase, which plays a role in neurotransmitter catabolism.

Uses

4-(4-Aminophenyl)butyric Acid is a degradation product of Chlorambucil (C325050); an alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin''s lymphoma (NHL) and Hodgkin''s disease.

4-(4-Aminophenyl)butyric acid(15118-60-2)Related Product Information

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