Isorhamnetin 3,7-O-diglucoside
Isorhamnetin 3,7-O-diglucoside Basic information
- Product Name:
- Isorhamnetin 3,7-O-diglucoside
- Synonyms:
-
- Isorhamnetin 3,7-O-diglucoside
- Isorhamnetin-3,7-diglucoside
- isorhamnetin 3,7-O-di-β-D-glucopyranoside
- Isorhamnetin-3,7-O-β-diglucopyranoside
- Isorhamnetin 3,7-di-O-β-D-glucopyranoside
- 4H-1-Benzopyran-4-one, 3,7-bis(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-
- CAS:
- 6758-51-6
- MF:
- C28H32O17
- MW:
- 640.55
- Mol File:
- 6758-51-6.mol
Isorhamnetin 3,7-O-diglucoside Chemical Properties
- Boiling point:
- 1016.2±65.0 °C(Predicted)
- Density
- 1.79±0.1 g/cm3(Predicted)
- pka
- 5.77±0.40(Predicted)
- form
- Solid
- color
- Off-white to light yellow
Isorhamnetin 3,7-O-diglucoside Usage And Synthesis
Uses
Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant[1].
in vivo
Isorhamnetin 3,7-di-O-β-D-glucopyranoside (10 or 20 mg/kg of body weight/day for 10 days; p.o.) to rats with streptozotocin-induced diabetes significantly reduced serum levels of glucose and 5-(hydroxymethyl)furfural (5-HMF), which is glycosylated with hemoglobin and is an indicator of oxidative stress[1].
| Animal Model: | Male Wistar rats (5 weeks old, 120-130 g) (STZ-induced diabetic rats had higher glucose and 5-HMF levels than normal rats)[1] |
| Dosage: | 10 or 20 mg/kg of body weight |
| Administration: | P.o.; daily for 10 days |
| Result: | The serum glucose levels of rats given 10 and 20 mg of orally were 510.1 and 492.4 mg/dL, respectively, whereas the control level was 574.2 mg/dL. |
References
[1] Yokozawa T, et al. Antioxidant effects of isorhamnetin 3,7-di-O-beta-D-glucopyranoside isolated from mustard leaf (Brassica juncea) in rats with streptozotocin-induced diabetes. J Agric Food Chem. 2002;50(19):5490-5495. DOI:10.1021/jf0202133
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Isorhamnetin 3,7-O-diglucoside(6758-51-6)Related Product Information
- ASTRAGALOSIDE
- IsorhaMnetin 3-sophoroside-7-rhaMnoside
- Isorhamnetin 3-glucuronide
- BRASSIDIN
- Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside
- 3-(6-O-α-L-Rhamnopyranosyl-β-D-galactopyranosyloxy)-3'-methoxy-4',5,7-trihydroxyflavone
- ISORHAMNETIN-3-GLUCOSIDE
- Isorhamnetin 3-O-α-L-arabinoside-7- O-α-L-rhamnoside
- Artemether
- hydroxygenkwanin
- (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one
- MOSLOFLAVONE
- Hydroxyecdysone
- alpha-Cyperone
- alpha-Terpineol
- beta-Eudesmol
- 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
- beta-Sitosterol