Tri-tert-butylphosphine Chemical Properties

Melting point:

30-35 °C(lit.)

Boiling point:

102-103 °C13 mm Hg(lit.)

Density 

0.861 g/mL at 25 °C

Flash point:

1 °F

storage temp. 

Flammables area

form 

solid

Specific Gravity

0.68

Water Solubility 

insoluble

Sensitive 

Air & Moisture Sensitive

Hydrolytic Sensitivity

9: reacts extremely rapidly with atmospheric moisture - may be pyrophoric - glove box or sealed system required

BRN 

1738613

InChIKey

BWHDROKFUHTORW-UHFFFAOYSA-N

CAS DataBase Reference

13716-12-6(CAS DataBase Reference)

NIST Chemistry Reference

Tri-tert-butylphosphine(13716-12-6)

Safety Information

Hazard Codes 

F,C

Risk Statements 

17-34-67-65-63-48/20-11

Safety Statements 

26-45-62-36/37/39-25-43-27-16

RIDADR 

UN 2846 4.2/PG 1

WGK Germany 

3

F 

10-19-23

HazardClass 

4.2

PackingGroup 

I

HS Code 

29319090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Tri-tert-butylphosphine Usage And Synthesis

Reaction

Useful as a ligand in a variety of palladium-catalyzed C-N, C-O and C-C bond-forming reactions under mild conditions.

Chemical Properties

Colorless to light yellow liqui

Uses

Tri-tert-butylphosphine is used primarily in the preparation of mono- and bidentate phosphine ligands in metal complexes for catalytic chiral asymmetric hydrogenations and other asymmetric reactions as well as transition metal coupling reactions. This reagent is also used in the preparation of other phosphines in catalytic polymerization reactions.

Uses

Valuable ligand for several coupling reactions. This product is offered as the THF solution for more convenient handling.

reaction suitability

reagent type: ligand
reaction type: Addition Reactions
reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reagent type: ligand
reaction type: Heck Reaction
reagent type: ligand
reaction type: Negishi Coupling
reagent type: ligand
reaction type: Sonogashira Coupling
reagent type: ligand
reaction type: Stille Coupling
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

Tri-tert-butylphosphine(13716-12-6)Related Product Information

• BIS-Tris
• tert-Butanol
• Tetrabutylammonium bromide
• BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE)
• tert-Butyl peroxyacetate
• Tricine
• Tris(hydroxymethyl)aminomethane
• 1,3,5-Tri-tert-butylbenzene
• Tributylphosphine
• tert-Butyl acetate
• T-BUTYLPHOSPHINE
• TRI-TERT-BUTYLPHOSPHONIUM TETRAPHENYLBORATE
• Tri-tert-butylphosphine tetrafluoroborate
• TRI-N-OCTYLPHOSPHINE
• TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
• TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA
• Triphenylene
• Hexafluoroacetone trihydrate