S(-)-RACLOPRIDE L-TARTRATE Chemical Properties

Melting point:

52.0 to 56.0 °C

Boiling point:

420.3±45.0 °C(Predicted)

Density 

1.288±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,2-8°C

solubility 

H₂O: 89 mg/mL

form 

solid

pka

5.93±0.50(Predicted)

color 

white

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

CV3465000

HS Code 

2933.99.8290

MSDS

• Language:English Provider:SigmaAldrich

S(-)-RACLOPRIDE L-TARTRATE Usage And Synthesis

Description

Raclopride is a selective dopamine D₂/D₃ receptor antagonist with K_i values of 1.8, 3.5, 2,400, and 18,000 nM for D₂, D₃, D₄, and D₁ receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease.

Chemical Properties

Yellowish solid

Uses

A labelled dopamine receptor

Uses

neuroleptic;selective dopamine D1/D2 receptors antagonist

Uses

Raclopride is a potent D2DR/D3DR antagonist.

Definition

ChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides.

Biological Activity

Selective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo .

storage

Store at -20°C

S(-)-RACLOPRIDE L-TARTRATE(84225-95-6)Related Product Information

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• S(-)-RACLOPRIDE L-TARTRATE
• Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:)
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• (S)-3,5-DICHLORO-N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2,6-DIHYDROXY-BENZAMIDE
• N-(5-chloro-2-methoxybenzyl)-N-ethylamine
• 2,4-Dichloro-5-methoxyphenol
• BENZAMIDE, N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-2-HYDROXY-6-METHOXY-, (S)-
• N-(3-CHLOROBENZYL)BUTAN-1-AMINE
• N-(5-CHLORO-2-METHOXYBENZYL)-N-METHYLAMINE
• 3,5-DICHLORO-2-HYDROXYBENZYLAMINE
• S(-)RACLOPRIDE L-TARTRATE >97% SELECTIVE D2 DOPAMINE
• N1-BENZYL-N2,N2-DIETHYL-1,2-PROPANEDIAMINE
• (S)-RACLOPRIDE, [METHOXY-3H]