(-)-PERILLYL ALCOHOL Chemical Properties

Boiling point:

119-121 °C11 mm Hg(lit.)

alpha 

-101o (NEAT)

Density 

0.96 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.501

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly), Methanol (Sparingly)

pka

14.85±0.10(Predicted)

form 

Liquid

color 

Colourless

Specific Gravity

0.960

optical activity

[α]22/D 88°, c = 1 in methanol

BRN 

2501605

LogP

3.077 (est)

CAS DataBase Reference

18457-55-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

37/38-41-36/37/38

Safety Statements 

26-39-36

WGK Germany 

3

RTECS 

OS8395000

F 

10

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

(-)-PERILLYL ALCOHOL Usage And Synthesis

Description

(–)-Perillyl alcohol is a monoterpene alcohol that has been found in lavender essential oil and has diverse biological activities. It reduces production of hydroperoxidienes and thiobarbituric acid reactive substances (TBARS) in vitro in a concentration-dependent manner. (–)-Perillyl alcohol inhibits PANC-1 pancreatic carcinoma cell and H-Ras-transformed fibroblast growth when used at a concentration of 1 mM. It also inhibits the growth of P. aeruginosa, E. coli, S. aureus, and C. albicans (MICs = 480-2,900 ppm).

Uses

(-)-Perillyl Alcohol is a monoterpene that induces apoptosis in colon tumor cells. Also, it is used in preparation of terpene-vanilloid conjugates as anti-inflammatory agents.

Definition

ChEBI: (S)-(-)-perillyl alcohol is a perillyl alcohol in which the chiral centre has S configuration. It is an enantiomer of a (R)-(+)-perillyl alcohol.

General Description

(S)-(-)-Perillyl alcohol is a monoterpenoid compound found in the essential oils of cherries, lavender and spearmint. It shows potent anticancer activity.

(-)-PERILLYL ALCOHOL(18457-55-1)Related Product Information

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