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MARTYNOSIDE

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MARTYNOSIDE Basic information

Product Name:
MARTYNOSIDE
Synonyms:
  • MARTYNOSIDE
  • 1-O-(3-Hydroxy-4-methoxyphenethyl)-3-O-(α-L-rhamnopyranosyl)-β-D-glucopyranose 4-(3-methoxy-4-hydroxy-trans-cinnamate)
  • 2-(3-Hydroxy-4-methoxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-4-O-[(E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl]-β-D-glucopyranoside
  • 3-Hydroxy-4-methoxyphenethyl 3-O-α-L-rhamnopyranosyl-4-O-(3-methoxy-4-hydroxy-trans-cinnamoyl)-β-D-glucopyranoside
  • Martyside
  • β-D-Glucopyranoside, 2-(3-hydroxy-4-methoxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate]
  • (2R,3R,4R,5R,6R)-5-hydroxy-6-[2-(3-hydroxy-4-methoxyphenyl)ethoxy]-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl](E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
CAS:
67884-12-2
MF:
C31H40O15
MW:
652.64
Mol File:
67884-12-2.mol
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MARTYNOSIDE Chemical Properties

Boiling point:
865.1±65.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
9.73±0.31(Predicted)
color 
White to off-white
InChIKey
WLWAYPFRKDSFCL-OQPPUVGONA-N
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MARTYNOSIDE Usage And Synthesis

Uses

Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU)-induced cell death and inflammation response by down-regulating the TNF signaling pathway[1].Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels

target

Estrogen receptor | ROS | Progestogen receptor

References

[1] Hong M, et al. Ex vivo and in vivo chemoprotective activity and potential mechanism of Martynoside against 5-fluorouracil-induced bone marrow cytotoxicity.?Biomed Pharmacother. 2021;138:111501. DOI:10.1016/j.biopha.2021.111501
[2] Papoutsi Z,et al. Acteoside and martynoside exhibit estrogenic/antiestrogenic properties.?J Steroid Biochem Mol Biol. 2006;98(1):63-71. DOI:10.1016/j.jsbmb.2005.07.005

MARTYNOSIDESupplier

Shanghai YuanYe Biotechnology Co., Ltd. Gold
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BioBioPha Co., Ltd.
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0871-65217109 13211707573;
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Shanghai T&W Pharmaceutical Co., Ltd.
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Shanghai Macklin Biochemical Co.,Ltd.
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15221275939
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shenlinxing@macklin.cn
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