NDRG3 Antibody Usage And Synthesis

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

The NDRG family consisting of NDRG1, NDRG2, NDRG3, and NDRG4 are structurally related proteins with roles in cell proliferation, differentiation, apoptosis, stress responses, and cell migration/metastasis. NDRG1 was originally identified as a protein that was upregulated in N-Myc knockout mice. Proteins in the NDRG family, particularly NDRG1 and NDRG2, have been reported to be down-regulated in various cancer tissues and have been suggested to function as a tumor suppressors.Members of the NDRG family each have distinct expression patterns; NDRG3 is most highly expressed in the testis, prostate, ovary, and brain. NDRG3 has also been shown to be up-regulated by androgen in prostate cell lines and can promote cell growth in those cells.

References

[1] Shimono, A. et al. (1999) Mech Dev 83, 39-52.
[2] Qu, X. et al. (2002) Mol Cell Biochem 229, 35-44.
[3] Zhou, R.H. et al. (2001) Genomics 73, 86-97.
[4] Yao, L. et al. (2008) Acta Biochim Biophys Sin (Shanghai) 40, 625-35.
[5] Ellen, T.P. et al. (2008) Carcinogenesis 29, 2-8.
[6] Okuda, T. and Kondoh, H. (1999) Biochem Biophys Res Commun 266, 208-15.
[7] Zhao, W. et al. (2001) Biochim Biophys Acta 1519, 134-8.
[8] Wang, W. et al. (2009) Int J Cancer 124, 521-30.

NDRG3 Antibody()Related Product Information

• Mouse Monoclonal GKAP Antibody
• Mouse Monoclonal TNFRSF11B Antibody
• CDK5 antibody
• HIF1A antibody
• MMP 1 antibody
• PRKDC antibody
• BMPR2 antibody
• MAP2K4 antibody
• CRK antibody
• CRTC3 Antibody