Palmitoyl chloride Chemical Properties

Melting point:

11-13 °C (lit.)

Boiling point:

88-90 °C/0.2 mmHg (lit.)

Density 

0.906 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.452(lit.)

Flash point:

>230 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly)

form 

Liquid

Specific Gravity

0.905

color 

Clear

Water Solubility 

Decomposition

Sensitive 

Moisture Sensitive

BRN 

972409

Stability:

Moisture Sensitive

CAS DataBase Reference

112-67-4(CAS DataBase Reference)

NIST Chemistry Reference

Palmitoyl chloride(112-67-4)

EPA Substance Registry System

Hexadecanoyl chloride (112-67-4)

Safety Information

Hazard Codes 

C

Risk Statements 

14-34-29

Safety Statements 

26-36/37/39-43-45-8

RIDADR 

UN 3265 8/PG 2

WGK Germany 

1

F 

9-21

TSCA 

Yes

HS Code 

2915 90 70

HazardClass 

8

PackingGroup 

II

Hazardous Substances Data

112-67-4(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: > 2000 mg/kg

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Palmitoyl chloride Usage And Synthesis

Chemical Properties

clear liquid

Uses

Palmitoyl Chloride was used as a polymeric carriers for plasmid DNA (pDNA) delivery to 293T cells.

Uses

Palmitoyl chloride is a compound which has been used as a polymeric carrier for plasmid DNA delivery to 293T cells.

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 6101, 1989 DOI: 10.1021/jo00287a023

General Description

A clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12°C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.

Air & Water Reactions

Decomposes rather slowly in water to form hydrochloric acid and palmitic acid, a fatty acid that is not soluble in water.

Reactivity Profile

HEXADECANOYL CHLORIDE is incompatible with bases (including amines), with strong oxidizing agents, and with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Flammability and Explosibility

Not classified

Palmitoyl chloride(112-67-4)Related Product Information

• Chloroacetyl chloride
• Oxalyl chloride
• Benzenesulfonyl chloride
• Benzoyl chloride
• Propionyl chloride
• Polyvinyl chloride
• Ammonium chloride
• Calcium chloride
• Pivaloyl chloride
• Tosyl chloride
• Sodium chloride
• Choline chloride
• Potassium chloride
• Thionyl chloride
• Sulfuryl chloride
• Sodium Palmitate
• PALM OIL
• Fatty acids, palm-oil