1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE Chemical Properties

Melting point:

186 °C

Boiling point:

506.7±50.0 °C(Predicted)

Density 

1.165±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), Dichloromethane (Slightly)

form 

Solid

pka

7.69±0.10(Predicted)

color 

Dark Purple to Dark Grey

InChI

InChI=1S/C17H21N3O/c1-21-17-8-6-16(7-9-17)20-12-10-19(11-13-20)15-4-2-14(18)3-5-15/h2-9H,10-13,18H2,1H3

InChIKey

VXEGSRKPIUDPQT-UHFFFAOYSA-N

SMILES

C1(N)=CC=C(N2CCN(C3=CC=C(OC)C=C3)CC2)C=C1

CAS DataBase Reference

74852-62-3(CAS DataBase Reference)

Safety Information

HS Code 

2933599590

1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE Usage And Synthesis

Chemical Properties

Purple Solid

Uses

4-[4-(4-Methyloxy-phenyl)-piperazin-1-yl]-phenylamine, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.

1-(4-AMINOPHENYL)-4-(4-METHOXYPHENYL)PIPERAZINE(74852-62-3)Related Product Information

• 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
• HYDROXY ITRACONAZOLE
• Itraconazole
• trans-Itraconazole
• N-Desalkyl Itraconazole
• Itraconazole Impurity 34
• Butyl Itraconazole
• 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-
• 1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylMethyl)-1,3-dioxolan-4-yl]Methoxy]phenyl]-4-(4-nitrophenyl)piperazine
• cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl benzoate
• Des-(1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one) Itraconazole
• 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE
• Propyl Itraconazole
• (1,2,4-Triazol-4-yl) Itraconazole
• cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate
• Itraconazole Impurity 15
• cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate
• cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol