N-Ethyl-N-hydroxyethylaniline Chemical Properties

Melting point:

36-38 °C (lit.)

Boiling point:

268 °C (lit.)

Density 

1.02

vapor pressure 

1Pa at 25℃

refractive index 

1.5605-1.5625

Flash point:

120 °C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Liquid

pka

14.66±0.10(Predicted)

color 

Clear colorless to yellow to orange, product may darken in storage

Water Solubility 

4.975g/L(20 ºC)

InChIKey

HYVGFUIWHXLVNV-UHFFFAOYSA-N

LogP

1.88 at 20℃

CAS DataBase Reference

92-50-2(CAS DataBase Reference)

NIST Chemistry Reference

Ethanol, 2-(ethylphenylamino)-(92-50-2)

EPA Substance Registry System

Ethanol, 2-(ethylphenylamino)- (92-50-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38-36

Safety Statements 

36/37/39-39-26

WGK Germany 

2

RTECS 

KL0878000

HS Code 

29221990

MSDS

• Language:English Provider:2-(N-Ethylanilino)ethanol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

N-Ethyl-N-hydroxyethylaniline Usage And Synthesis

Chemical Properties

clear yellow liquid after melting

Uses

2-(N-Ethylanilino) ethanol was used in the preparation of azo compound N-ethyl-N-(2-hydroxylethyl)-4-(2-cyano-4-nitrophenylazo) aniline (AZ1)².

General Description

2-(N-Ethylanilino) ethanol couples with 2-amino-5-formylthiophene during the synthesis of nonlinear optical chromophores. It undergoes azo coupling with 2-cyan-4-nitroaniline to yield azochromophore AZ1.

Synthesis

1. The autoclave was purged with nitrogen and protected by nitrogen with 24.2 kg (200 mol) of N-ethylaniline, 8.9 kg (202 mol) of ethylene oxide, and 242 g (1.9 mol) of taurine. 2. The autoclave was closed, making sure that the lid was screwed on tightly. 3. The heating system was turned on, and the temperature was ramped up to 102°C at a rate of 1°C/min before stopping the heating, and the temperature of the reaction will naturally rise to 133°C. 4. Maintain the reaction at 133°C for 4 h. 5. Upon completion of the reaction, the reaction mixture was cooled to 40°C. 6. Open the autoclave and collect the product to give 32.8 kg of N-ethyl-N-hydroxyethylaniline in 99.4% yield.

References

[1] Patent: CN108117492, 2018, A. Location in patent: Paragraph 0050; 0052; 0054; 0056; 0057; 0058
[2] Journal of the American Chemical Society, 1944, vol. 66, p. 1640
[3] Bulletin de la Societe Chimique de France, 1927, vol. <4>41, p. 937

N-Ethyl-N-hydroxyethylaniline(92-50-2)Related Product Information

• Ethyl formate
• Ethyl acetate
• 2-Hydroxyethanesulphonic acid
• Hydroxyethyl Cellulose
• 2-Ethylaniline
• 3-METHYL-N-ETHYL-N'-HYDROXYETHYLANILINE
• 2-(2-Aminoethylamino)ethanol
• Ethylparaben
• 3-Ethylanilinopropiononitrile
• Ethanol
• Ethyl acrylate
• Hydroxyethyl starch
• Ethyl cellulose
• CHLOROETHANE
• Ethylbenzene
• 2-Methoxyethanol
• N-Ethylaniline
• Sodium isethionate