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PROCYANIDIN C1

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PROCYANIDIN C1 Basic information

Product Name:
PROCYANIDIN C1
Synonyms:
  • PROCYANIDIN C1
  • (4,8’:4’,8’’-ter-2h-1-benzopyran)-3,3’,3’’,5,5’,5’’,7,7’,7’’-nonol,2,2’,2’’-tr
  • 4-dihydroxyphenyl)-3,3’,3’’,4,4’,4’’-hexahydro-is(stereoisomer
  • procyanidolc1
  • (2R,3R,4S)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol
  • (2R,3R,4S)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-8-yl]-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-yl]chromane-3,5,7-triol
  • PROCYANIDIN B2(P)
  • 4,8:4,8-Ter-2H-1-benzopyran-3,3,3,5,5,5,7,7,7-nonol, 2,2,2-tris(3,4-dihydroxyphenyl)-3,3,3,4,4,4-hexahydro-, (2R,2R,2R,3R,3R,3R,4R,4S)-
CAS:
37064-30-5
MF:
C45H38O18
MW:
866.77
Product Categories:
  • Catechins & Tannins
Mol File:
37064-30-5.mol
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PROCYANIDIN C1 Chemical Properties

Density 
1.747±0.06 g/cm3( 20 ºC : 760 Torr)
storage temp. 
-20°C
solubility 
Soluble in methan
pka
9.19±0.70(Predicted)
form 
Solid
color 
Beige-brown
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Safety Information

WGK Germany 
3
HS Code 
29329990
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PROCYANIDIN C1 Usage And Synthesis

Description

Procyanidin C1 is a polyphenol flavonoid trimer of (–)-epicatechin that has HIV-related and antioxidant activities. It activates latent HIV-1 provirus in JLR2 cells when used at concentrations ranging from 12.5 to 50 μM and increases NF-κB-dependent transcriptional activity in Jurkat T cells. Procyanidin C1 also scavenges 2,2’-diphenyl-1-picrylhydrazyl (DPPH) radicals (IC50 = 3.2 μg/ml) and inhibits the activity of α-glucosidase (IC50 = 3.8 μg/ml) and 15-lipoxygenase (15-LO; IC50 = 57.6 μg/ml). Procyanidin C1 (10 μg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells.

Definition

ChEBI: Procyanidin C1 is a proanthocyanidin consisting of three (-)-epicatechin units joined by two successive (4beta->8)-linkages. It has a role as a metabolite, an anti-inflammatory agent, an antioxidant, a lipoxygenase inhibitor, an EC 1.17.3.2 (xanthine oxidase) inhibitor and an EC 3.2.1.20 (alpha-glucosidase) inhibitor. It is a hydroxyflavan, a proanthocyanidin and a polyphenol. It is functionally related to a (-)-epicatechin.

PROCYANIDIN C1Supplier

Chengdu Push Bio-Technology Co., Ltd. Gold
Tel
18080489829
Email
3004654993@qq.com
Chengdu Caoyuankang Biological Technology Co., Ltd. Gold
Tel
134-38890071 13438890071
Email
3003796344@qq.com
Chengdu Nakeli Biotechnology Co., Ltd. Gold
Tel
028-61983833 19138982515
Email
3265827856@qq.com
Hubei CuiRan Biotechnology Co., Ltd. Gold
Tel
18162791556
Email
3152548389@qq.com
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Email
y.liu@mail.biobiopha.com
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