Basic information Safety Supplier Related

N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE

Basic information Safety Supplier Related

N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE Basic information

Product Name:
N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE
Synonyms:
  • N-Ethyl-N-(2-hydroxyethyl)nitrous amide
  • 2-(Ethylnitrosoamino)ethanol
  • Ethanol,2-(ethylnitrosoamino)
  • ethyl-2-hydroxyethylnitrosamine
  • n-ethyl-n-hydroxyethylnitrosamine
  • n-nitrosoaethylaethanolamin
  • C023845
  • N-Ethyl-N-(2-hydroxyethyl)nitrosamine
CAS:
13147-25-6
MF:
C4H10N2O2
MW:
118.13
Mol File:
13147-25-6.mol
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N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE Chemical Properties

Boiling point:
103 °C / 3mmHg
Density 
1.2188 (rough estimate)
refractive index 
1.4710 to 1.4750
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
clear liquid
color 
Light yellow to Amber to Dark green
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Safety Information

RTECS 
KL0350000
HS Code 
2928.00.5000
Toxicity
LD50 oral in rat: > 7500mg/kg
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N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE Usage And Synthesis

Uses

N-Ethyl-N-(2-hydroxyethyl)nitrosamine is a member of the nitrosamine class of carcinogens and induces renal cancer. It has been shown to induce tumors in the kidneys of rats and in the lungs of mice.

Definition

ChEBI: N-ethyl-N-(2-hydroxyethyl)nitrosamine is a nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents. It has a role as a carcinogenic agent. It is a nitrosamine and a primary alcohol. It is functionally related to a N-nitrosodiethylamine.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. Explodes when heated to 170℃. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

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