Methyl 3-hydroxypropanoate Chemical Properties

Melting point:

147-148 °C(Solv: benzene (71-43-2); cyclohexane (110-82-7))

Boiling point:

179°C (estimate)

Density 

1.1050

refractive index 

1.4300

storage temp. 

2-8°C

solubility 

Chloroform, Methanol

form 

Oil

pka

13.89±0.10(Predicted)

color 

Colourless

InChI

InChI=1S/C4H8O3/c1-7-4(6)2-3-5/h5H,2-3H2,1H3

InChIKey

RVGLEPQPVDUSOJ-UHFFFAOYSA-N

SMILES

C(OC)(=O)CCO

Safety Information

HazardClass 

IRRITANT

HS Code 

2918199890

Methyl 3-hydroxypropanoate Usage And Synthesis

Definition

ChEBI: 2-Methyl-3-hydroxypropanoate is a 3-hydroxy carboxylic acid.

General Description

Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Methyl 3-hydroxypropanoate(6149-41-3)Related Product Information

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