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ALISOL ACETATE B

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ALISOL ACETATE B Basic information

Product Name:
ALISOL ACETATE B
Synonyms:
  • ALISOL ACETATE B
  • (8α,9β,14β)-23-Acetoxy-11β-hydroxy-dammar-13(17)-ene-3,24-dione
  • (8alpha,9beta,14beta)-23-Acetoxy-11beta-hydroxy-dammar-13(17)-ene-3,24-dione
  • 23-ACETATE ALISOL B
  • 8α,9β,14β-Dammar-13(17)-ene-3,24-dione, 11β,23-dihydroxy-, 23-acetate, (+)- (8CI)
  • ALISOL ACETATE B USP/EP/BP
CAS:
19865-76-0
MF:
C32H50O5
MW:
514.74
Product Categories:
  • Miscellaneous Natural Products
Mol File:
19865-76-0.mol
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ALISOL ACETATE B Chemical Properties

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
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ALISOL ACETATE B Usage And Synthesis

Description

Alisol B acetate can induce Bax nuclear translocation and apoptosis in human hormone-resistant prostate cancer PC-3 cells, the Bax activation and translocation from the cytosol to nucleus might be a crucial response to the apoptotic effect. Alisol B acetate exhibits an antiproliferative effect in SGC7901 cells by inducing apoptosis, apoptosis of SGC7901 cells involves mitochondria-caspase and PI3K/Akt dependent pathways.

Uses

Alisol B acetate is a Triterpenoids product that can be isolated from the tubers of Alisma plantago-aquatica Linn.[1].

Definition

ChEBI: Alisol b acetate is a triterpenoid.

References

[1] Xu YH, et al. Alisol B acetate induces apoptosis of SGC7901 cells via mitochondrial and phosphatidylinositol 3-kinases/Akt signaling pathways. World J Gastroenterol. 2009 Jun 21;15(23):2870-7. DOI:10.3748/wjg.15.2870

ALISOL ACETATE BSupplier

Chengdu Herbpurify Co.Ltd.
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