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8-Hydroxyquinoline sulfate monohydrate

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8-Hydroxyquinoline sulfate monohydrate Basic information

Product Name:
8-Hydroxyquinoline sulfate monohydrate
Synonyms:
  • 8-QUINOLINOL SULFATE MONOHYDRATE
  • 8-QUINOLINOL HEMISULFATE HEMIHYDRATE
  • 8-QUINOLINOL HEMISULFATE SALT HEMIHYDRATE
  • 8-HYDROXYQUINOLINE HEMISULFATE HEMIHYDRATE
  • 8-HYDROXYQUINOLINE HEMISULFATE SALT HEMIHYDRATE
  • 8-HYDROXYQUINOLINE SULPHATE MONOHYDRATE
  • 8-HYDROXYQUINOLINE SULFATE MONOHYDRATE
  • OXINE SULFATE MONOHYDRATE
CAS:
207386-91-2
MF:
C9H11NO6S
MW:
261.25
EINECS:
677-811-7
Mol File:
207386-91-2.mol
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8-Hydroxyquinoline sulfate monohydrate Chemical Properties

Melting point:
176-179 °C(lit.)
storage temp. 
Store below +30°C.
solubility 
H2O: soluble100mg/mL, clear to slightly hazy, yellow to orange
form 
Crystalline Powder or Lumps
color 
Yellow
PH
3.2 (H2O, 20℃)
Water Solubility 
soluble
Merck 
13,4869
BRN 
3760550
InChI
InChI=1S/C9H7NO.H2O4S.H2O/c11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4;/h1-6,11H;(H2,1,2,3,4);1H2
InChIKey
SJMNPMHTETVUOH-UHFFFAOYSA-N
SMILES
N1C2C(=CC=CC=2O)C=CC=1.S(O)(O)(=O)=O.[H]O[H]
CAS DataBase Reference
207386-91-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
WGK Germany 
3
RTECS 
VC8260000
TSCA 
Yes
HS Code 
2933 49 90
Toxicity
LD50 orally in Rabbit: 1200 mg/kg LD50 dermal Rat > 4000 mg/kg

MSDS

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8-Hydroxyquinoline sulfate monohydrate Usage And Synthesis

Chemical Properties

yellow crystalline powder or lumps

Uses

8-Hydroxyquinoline Hemisulfate Salt Hemihydrate is a 20S proteasome inhibitor. It can be used in pharmacological activity and biological study of treatment of drug-resistant bacterial and fungal infections with metal chelating compounds such as clioquinol analogs and combination with other antibiotics in relation to β lactamase.

Biochem/physiol Actions

It is a potential copper ligand and is a tested effective proteasome inhibitor.

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