1-PHENYL-3-BUTEN-1-OL Chemical Properties

Boiling point:

234 °C (lit.)

Density 

0.992 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.53(lit.)

Flash point:

217 °F

form 

Liquid

pka

14.22±0.20(Predicted)

color 

Clear colorless

Safety Information

WGK Germany 

2

HS Code 

29062900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

1-PHENYL-3-BUTEN-1-OL Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

4-Phenyl-1-buten-4-ol is a building block that can be used in the synthesis of (R)-2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one (H447850), which is an impurity of Propafenone (P757500), a sodium channel blocker and an antiarrhythmic (class IC) compound.

Definition

ChEBI: 1-phenyl-3-buten-1-ol is an aromatic alcohol that is (but-3-en-1-yl)benzene in which one of the benzylic methylene hydrogens has been replaced by a hydroxy group. It is a secondary alcohol, an aromatic alcohol and an olefinic compound.

Synthesis Reference(s)

Chemistry Letters, 17, p. 2049, 1988
Journal of the American Chemical Society, 110, p. 4473, 1988 DOI: 10.1021/ja00221a091
Tetrahedron Letters, 30, p. 5413, 1989 DOI: 10.1016/S0040-4039(01)80581-5

1-PHENYL-3-BUTEN-1-OL(936-58-3)Related Product Information

• 3-Buten-1-ol
• Propafenone DiMer IMpurity-d10
• 1-(2-hydroxyphenyl)-3-(2,3,4,5,6-pentadeuteriophenyl)propan-1-one
• DepropylaMino Chloro Propafenone-d5
• Flavanone-d5
• Propafenone D7 hydrochloride
• N-Depropyl Propafenone-D5 Oxalate Salt
• (2E)-Dehydro Propafenone-d5 Hydrochloride
• Propafenone Impurity 48
• 1-[2-[1,1,2,3,3-pentadeuterio-2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propoxy]phenyl]-3-phenylpropan-1-one
• 5-Hydroxy Propafenone-D5 Hydrochloride
• XWIHRGFIPXWGEF-LUIAAVAXSA-N
• Propafenone Impurity 49
• DepropylaMino Hydroxy Propafenone-d5
• 1-[2-(OxiranylMethoxy)-5-(benzyloxy)phenyl]-3-phenyl-2-propen-1-one
• 2’-(2,3-EpoxypropoxyD5)-3-phenyl-propiophenone
• 5-HYDROXY PROPAFENONE HYDROCHLORIDE
• 4-Phenyl-1-butene