3-Cyclohexylaminopropanesulfonic Acid
3-Cyclohexylaminopropanesulfonic Acid Basic information
- Product Name:
- 3-Cyclohexylaminopropanesulfonic Acid
- Synonyms:
-
- N-Cyclohexyl-3-aMinopropanesulfonic acid (CAPS)
- CAPS, free acid
- BRAND? push-on cap for Technicon Analyzer
- Push-on caps
- BRAND? combi-pack caps and seal for Transferpette
- Seals
- BRAND? strip of 8 lids, for 96 tube rack
- BRAND? cap for UV-cuvette micro
- CAS:
- 1135-40-6
- MF:
- C9H19NO3S
- MW:
- 221.32
- EINECS:
- 214-492-1
- Product Categories:
-
- Pharmaceutical Intermediates
- buffer
- Mol File:
- 1135-40-6.mol
3-Cyclohexylaminopropanesulfonic Acid Chemical Properties
- Melting point:
- >300 °C(lit.)
- Density
- 1.1809 (rough estimate)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.5250 (estimate)
- Flash point:
- >110℃
- storage temp.
- room temp
- solubility
- H2O: 0.5 M at 20 °C, clear
- form
- Powder/Solid
- color
- White
- Odor
- Odorless
- PH Range
- 3 - 7
- PH
- 3.0-7.0 (20℃, 0.5M in H2O)
- pka
- 10.4(at 25℃)
- Water Solubility
- 9 g/100 mL (20 ºC)
- λmax
- λ: 260 nm Amax: ≤0.04
λ: 280 nm Amax: ≤0.04 - Merck
- 14,1767
- BRN
- 2835588
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- 0.3 at 25℃
- CAS DataBase Reference
- 1135-40-6(CAS DataBase Reference)
- EPA Substance Registry System
- 1-Propanesulfonic acid, 3-(cyclohexylamino)- (1135-40-6)
Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/38-36/37/38-22-20/21/22-40/22
- Safety Statements
- 26-36/37/39-37/39-24/25-22-23-36
- WGK Germany
- 3
- RTECS
- TZ6395000
- F
- 34
- TSCA
- Yes
- HS Code
- 29213099
MSDS
- Language:English Provider:3-(Cyclohexylamino)-1-propanesulfonic acid
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
3-Cyclohexylaminopropanesulfonic Acid Usage And Synthesis
Chemical Properties
White/clear crystalline powder
Description
3-Cyclohexylaminopropanesulfonic Acid, also known as 3-(Cyclohexylamino)-1-propanesulfonic acid (CHAPS) or N-Cyclohexyl-3-aminopropanesulfonic acid, is a detergent with a high affinity for basic proteins that can be used to extract these proteins from biological samples and solubilize them. CHAPS is a type of ampholyte, which means it has both anionic and cationic groups.
Uses
3-Cyclohexylaminopropanesulfonic Acid buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718, sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good's buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects. It is a biological buffer.
Definition
ChEBI: Cyclohexylaminopropanesulfonic acid is an amine.
Flammability and Explosibility
Not classified
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