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8-HYDROXYGUANOSINE

Basic information Safety Supplier Related

8-HYDROXYGUANOSINE Basic information

Product Name:
8-HYDROXYGUANOSINE
Synonyms:
  • 8-Oxo-D-guanosine
  • 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione
  • 2-amino-9-beta-d-ribofuranosylpurine-6,8(1h,9h)-dione
  • 7,8-dihydro-8-oxo-guanosin
  • 9h)-dione,2-amino-9-beta-d-ribofuranosyl-purine-8(1h
  • 8-HYDROXYGUANOSINE
  • 8-OHG
  • 8-OH-GUO
CAS:
3868-31-3
MF:
C10H13N5O6
MW:
299.24
Product Categories:
  • Carbohydrates & Derivatives
  • Metabolites & Impurities
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Labeling and Diagnostics Reagents
  • Nucleotides
Mol File:
3868-31-3.mol
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8-HYDROXYGUANOSINE Chemical Properties

Melting point:
232-235°C
Density 
2.43±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) Water (Slightly, Heated,Sonicated)
form 
White to off-white powder.
pka
7.75±0.20(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Safety Information

Toxicity
sce-hmn-lym 100 nmol/L MUREAV 403,223,1998
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8-HYDROXYGUANOSINE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro

Uses

It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells.

Definition

ChEBI: 8-Hydroxyguanosine is a purine nucleoside.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

8-HYDROXYGUANOSINESupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Hongene Biotech Corporation
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021-64757213
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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info@chemlin.com.cn
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com