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BOLDINE DIMETHYL ETHER

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BOLDINE DIMETHYL ETHER Basic information

Product Name:
BOLDINE DIMETHYL ETHER
Synonyms:
  • bromcholitin
  • d-glaucine
  • glauvent
  • (+)-GLAUCINE
  • GLAUCINE
  • BOLDINE DIMETHYL ETHER
  • 1,2,9,10-TETRAMETHOXYAPORPHINE
  • (S)-1,2,9,10-TETRAMETHOXY-6-METHYL-5,6,6A,7-TETRAHYDRO-4H-DIBENZO[DE,G]QUINOLINE
CAS:
475-81-0
MF:
C21H25NO4
MW:
355.43
EINECS:
207-501-5
Product Categories:
  • Heterocycles
Mol File:
475-81-0.mol
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BOLDINE DIMETHYL ETHER Chemical Properties

Melting point:
246-247℃
alpha 
D20 +115° (c = 3 in alc)
Boiling point:
488.45°C (rough estimate)
Density 
1.166±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.5614 (estimate)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
6.35±0.20(Predicted)
color 
Pale Beige
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BOLDINE DIMETHYL ETHER Usage And Synthesis

Description

Glaucine (Item No. 17338) is an analytical reference standard categorized as an antitussive. Glaucine has hallucinogenic properties. This product is intended for research and forensic applications.

Uses

d-Glaucine has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries.

Definition

ChEBI: (S)-glaucine is an aporphine alkaloid that is (S)-1,2,9,10-tetrahydroxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline in which the four phenolic hydrogens have been replaced by methyl groups. It has a role as a platelet aggregation inhibitor, a NF-kappaB inhibitor, an antitussive, an antibacterial agent, a muscle relaxant, an antineoplastic agent, a plant metabolite and a rat metabolite. It is an aporphine alkaloid, a polyether, an organic heterotetracyclic compound and a tertiary amino compound. It is a conjugate base of a (S)-glaucine(1+).

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