2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Chemical Properties

storage temp. 

Store at RT

solubility 

<20.27mg/ml in DMSO

form 

Powder

2-[[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL] METHYL]-6-METHYL-2,3-DIHYDROIMIDAZO[1,2C]QUINAZOLIN-5(6H)-ONE Usage And Synthesis

Uses

2-MPMDQ is a novel class of α1-adrenoceptor antagonists and acts as an anti-hypertensive agent.

Definition

ChEBI: 2-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]-6-methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5-one is a member of piperazines.

Biological Activity

Potent and selective α 1 -adrenoceptor antagonist; hypotensive.

References

[1]. chern jw, tao pl, yen mh, et al. studies on quinazolines. 5. 2,3-dihydroimidazo[1,2-c]quinazoline derivatives: a novel class of potent and selective alpha 1-adrenoceptor antagonists and antihypertensive agents. j med chem, 1993, 36(15): 2196-2207.