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5'-O-Dimethoxytrityl-deoxythymidine

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5'-O-Dimethoxytrityl-deoxythymidine Basic information

Product Name:
5'-O-Dimethoxytrityl-deoxythymidine
Synonyms:
  • 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE
  • 5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxythymidine
  • 5'-O-(4,4'-DIMETHOXYTRITYL)THYMIDINE
  • 5-O-(4,4-DIMETHOXYTRITYL)THYMIDINE
  • 5'-O-DIMETHOXYTRITYL-DEOXYTHYMIDINE
  • 5'-O-(DIMETHOXYTRITYL)-THYMIDINE
  • 5'-O-DMT-THYMIDINE
  • 5'-O-(p,p'-dimethoxytrityl)thymidine
CAS:
40615-39-2
MF:
C31H32N2O7
MW:
544.59
EINECS:
255-003-1
Product Categories:
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Nucleotides
  • PNS
Mol File:
40615-39-2.mol
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5'-O-Dimethoxytrityl-deoxythymidine Chemical Properties

Melting point:
114-116 °C (subl.)(lit.)
Boiling point:
618.41°C (rough estimate)
Density 
1.2483 (rough estimate)
vapor pressure 
0Pa at 20℃
refractive index 
7 ° (C=1, MeOH)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Powder
pka
9.55±0.10(Predicted)
color 
White to off-white
Water Solubility 
3mg/L at 20℃
BRN 
599297
Stability:
Store in Freezer
LogP
4.61 at 20℃
CAS DataBase Reference
40615-39-2(CAS DataBase Reference)
EPA Substance Registry System
Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
1-3-10
Hazard Note 
Irritant
HS Code 
29349990

MSDS

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5'-O-Dimethoxytrityl-deoxythymidine Usage And Synthesis

Chemical Properties

White Powder

Uses

5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies.

General Description

5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.

Flammability and Explosibility

Not classified

5'-O-Dimethoxytrityl-deoxythymidineSupplier

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