ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Basic information
- Product Name:
- 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
- Synonyms:
-
- 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
- DR 2313
- 7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
- 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
- 4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2
- 4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL-
- SC-202756
- 2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one
- CAS:
- 284028-90-6
- MF:
- C8H10N2OS
- MW:
- 182.24
- EINECS:
- 200-589-5
- Mol File:
- 284028-90-6.mol
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1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Chemical Properties
- Boiling point:
- 349.3±52.0 °C(Predicted)
- Density
- 1.46±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: >2mg/mL (warmed)
- form
- powder
- pka
- 1.54±0.20(Predicted)
- color
- white to beige
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1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE Usage And Synthesis
Biological Activity
Potent, competitive inhibitor of poly(ADP-ribose) polymerase (PARP) (IC 50 values are 0.20 and 0.24 μ M for PARP-1 and PARP-2 respectively). Neuroprotective; reduces neuronal cell death in models of cerebral ischemia in vivo and in vitro . Brain penetrant.
1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Shanghai Longsheng chemical Co.,Ltd.
- Tel
- 021-58099652-8005 13585536065
- bin.wu@shlschem.com
EnciPharmatech Co., Ltd
- Tel
- 025-52714267-66 13813902930
- stephen_shengll@hotmail.com
China Langchem Inc.
- Tel
- 0086-21-58956006
Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel
- 0571-82693216
- info@yuhaochemical.com
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1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE(284028-90-6)Related Product Information
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- 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE