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Scopine-2,2-dithienyl glycolate

Basic information Description Safety Supplier Related

Scopine-2,2-dithienyl glycolate Basic information

Product Name:
Scopine-2,2-dithienyl glycolate
Synonyms:
  • SCOPINE-2,2-DITHIENYL GLYCOLATE
  • (1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2,2-dithiophen-2-ylacetate
  • Tiotropium EP Impurity B
  • 2-Thiopheneacetic acid, -hydroxy--2-thienyl-, (1,2,4,5,7)
  • 2-thiopheneacetic acid, a-hydroxy-a-2th ( Di(2-thienyl) Glycolate )
  • N-DeMethyl TiotropiuM
  • α-Hydroxy-α-2-thienyl-2-thiopheneacetic Acid (1α,2β,4β,5α,7β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester
  • Scopine di(2-thienyl)glycolate scopine-2-dithienyl glycolate
CAS:
136310-64-0
MF:
C18H19NO4S2
MW:
377.48
EINECS:
603-953-6
Product Categories:
  • Heterocycles
  • Intermediates & Fine Chemicals
  • TIOTROPIUM BROMIDE
  • Pharmaceuticals
  • Tiotropium Bromide Intermediates
  • 136310-64-0
Mol File:
136310-64-0.mol
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Scopine-2,2-dithienyl glycolate Chemical Properties

Melting point:
138-140°C
Boiling point:
542.3±50.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
10.32±0.29(Predicted)
color 
White to Off-White
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Scopine-2,2-dithienyl glycolate Usage And Synthesis

Description

Scopine-2,2-dithienyl glycolate is an organic compound. It is off-white solid. The melting point is 138-140°C. The storage temperature is -20°C. Scopine-2,2-dithienyl glycolate is one of the reaction intermediates in the preparation of tiotropium bromide, which is a highly effective anticholinergic agent and widely used for treatment of asthma and/or chronic obstructive pulmonary disease (COPD) (chronic obstructive pulmonary disease).

Chemical Properties

Off-White Solid

Uses

Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.

Scopine-2,2-dithienyl glycolateSupplier

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