1,3-Difluorobenzene
1,3-Difluorobenzene Basic information
- Product Name:
- 1,3-Difluorobenzene
- Synonyms:
-
- 1,3-difluroethylene
- Benzene, m-difluoro-
- benzene,1,3-difluoro-
- Benzene,m-difluoro-
- Between two fluorine benzene
- 1,3-DifL
- Difluoro-1,3-benzene
- m-difluoro-benzen
- CAS:
- 372-18-9
- MF:
- C6H4F2
- MW:
- 114.09
- EINECS:
- 206-746-5
- Product Categories:
-
- Aryl Fluorinated Building Blocks
- Building Blocks
- Chemical Synthesis
- Fluorinated Building Blocks
- Halogenated Hydrocarbons
- Organic Building Blocks
- Aromatic Hydrocarbons (substituted) & Derivatives
- Fluorobenzene
- Fluorine Compounds
- Aryl
- C6
- Organic Fluorinated Building Blocks
- Other Fluorinated Organic Building Blocks
- alkyl Fluorine
- Halogenated Hydrocarbons
- bc0001
- K00001
- Mol File:
- 372-18-9.mol
1,3-Difluorobenzene Chemical Properties
- Melting point:
- -59 °C
- Boiling point:
- 83 °C
- Density
- 1.163 g/mL at 25 °C(lit.)
- vapor pressure
- 11.034-19.924kPa at 20-38.2℃
- refractive index
- n20/D 1.438(lit.)
- Flash point:
- 36 °F
- storage temp.
- Flammables area
- solubility
- 1.1g/l
- form
- Liquid
- Specific Gravity
- 1.163
- color
- Clear colorless to yellow
- Water Solubility
- insoluble
- BRN
- 1904537
- Dielectric constant
- 5.2400000000000002
- LogP
- 2.21-2.52 at 25℃ and pH6.5
- CAS DataBase Reference
- 372-18-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 1,3-difluoro-(372-18-9)
Safety Information
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20-2017/11/20
- Safety Statements
- 7-16-29-33-7/9
- RIDADR
- UN 1993 3/PG 2
- WGK Germany
- 1
- RTECS
- CZ5652000
- Hazard Note
- Highly Flammable
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29036990
MSDS
- Language:English Provider:1,3-Difluorobenzene
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
1,3-Difluorobenzene Usage And Synthesis
Synthesis
Higher yields were observed when CsF and HF were reacted with 1,3-dichlorobenzene,
which gave I ,3-difluorobenzene.
Chemical Properties
1,3-Difluorobenzene (C6H4F2, CAS registry No. 372-18-9) is also named as m-difluorobenzene, which is a clear colorless to yellowish liquid. Its melting point is -59 °C, boiling point is 83 °C and flash point is 2 oC. It is insoluble in water and stable under normal temperatures and pressures. It is toxic and flammable. It will produce toxic fluoride gas by heat.
Uses
1,3-Difluorobenzene has been extensively used in the synthesis of pharmaceutical and pesticide intermediate. For example, it can be used for the synthesis of fluorinated medicine such as Fluconazole, etc. and pesticide (Flucycloxuron, Diflubenzuro, etc.). It can also be used to synthesize liquid crystal materials.
Chemical Properties
CLEAR COLORLESS TO YELLOWISH LIQUID
Uses
It is used in the laser induced fluorencence matrix study of 1,3-difluorobenzene radical cation. It is also used synthesis of 1,2,3-triazole containing fluconazole analogues.
Definition
ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 3.
1,3-Difluorobenzene Preparation Products And Raw materials
Preparation Products
Raw materials
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1,3-Difluorobenzene (372-18-9)Related Product Information
- 2,6-Difluorophenol
- 4-Fluorobenzaldehyde
- α,α-Difluorophenylacetic acid
- Florfenicol
- 3,4-Difluorobenzonitrile
- 2,6-Difluorobenzamide
- 2,3-Difluorobenzoic acid
- Transfluthrin
- 2,3-Difluorophenol
- 2,6-Difluorobenzoic acid
- 2,6-Difluorobenzaldehyde
- 2,6-Difluorobenzonitrile
- 2-Difluorobenzene,1,2-Difluorobenzene 98%,1,2-Difluorobenzene,98+%,o-Difluorobenzene,99%
- Pentafluorobenzene
- DECAFLUOROBENZHYDROL
- 2',3',4',5',6'-PENTAFLUOROACETOPHENONE
- 2,3,4,5,6-PENTAFLUOROBENZOPHENONE
- DIPHENYL(PENTAFLUOROPHENYL)PHOSPHINE