4-Acetylbiphenyl Chemical Properties

Melting point:

152-155 °C(lit.)

Boiling point:

325-327 °C

Density 

1.2510

refractive index 

1.5920 (estimate)

Flash point:

168°C/8mm

storage temp. 

2-8°C

solubility 

chloroform: soluble10mg/200microlitres, clear, colorless to faintly yellow

form 

Solid

color 

White to Green to Brown

Water Solubility 

insoluble

BRN 

1101615

InChI

InChI=1S/C14H12O/c1-11(15)12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-10H,1H3

InChIKey

QCZZSANNLWPGEA-UHFFFAOYSA-N

SMILES

C(=O)(C1=CC=C(C2=CC=CC=C2)C=C1)C

CAS DataBase Reference

92-91-1(CAS DataBase Reference)

NIST Chemistry Reference

Ethanone, 1-[1,1'-biphenyl]-4-yl-(92-91-1)

EPA Substance Registry System

Ethanone, 1-[1,1'-biphenyl]-4-yl- (92-91-1)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

RTECS 

DI0887010

TSCA 

TSCA listed

HS Code 

29143900

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2

MSDS

• Language:English Provider:4-Phenylacetophenone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Acetylbiphenyl Usage And Synthesis

Chemical Properties

Off-white to beige powder

Uses

4-Acetylbiphenyl is involved in the study of inactivation of 7-ethoxy-4-trifluoromethylcoumarin ortho-deethylase activity by various arylalkynes. Further, it is used in the preparation of Schiffs base.

Uses

4-Acetylbiphenyl was used to study the inactivation of 7-ethoxy-4-trifluoromethylcoumarin O-deethylase activity by various arylalkynes. It may be used in the synthesis of Schiffs base.

Uses

Intermediates of Liquid Crystals

Synthesis

4-Acetylbiphenyl is a biphenyl compound that can be prepared from an aryl halide or trifluoroborate with an aryl boronic acid and a palladium catalyst by the Suzuki-Miyaura and Buchwald-Hartwig reaction.

Purification Methods

Crystallise it from EtOH or acetone. It can also be distilled under reduced or atmospheric pressure. The semicarbazone has m 131-132o (aqueous EtOH). [Beilstein 7 H 443, 7 III 2134, 7 IV 1407.]

4-Acetylbiphenyl(92-91-1)Related Product Information

• 3-Aminoacetophenone
• Methyl acrylate
• Dichloroacetonitrile
• Bifonazole
• 4,4'-Diacetylbiphenyl
• Bifenthrin
• Biphenyl
• 4'-Bromoacetophenone
• Acetylferrocene
• Kresoxim-methyl
• 4'-Methoxyacetophenone
• Methylparaben
• Methanol
• N-ACETYL-L-TYROSINE ETHYL ESTER
• 4-Nitroacetophenone
• 4'-Hydroxyacetophenone
• 4'-Methyl-2-cyanobiphenyl
• Acetonitrile