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2',3'-Dideoxy-2',3'-didehydroinosine

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2',3'-Dideoxy-2',3'-didehydroinosine Basic information

Product Name:
2',3'-Dideoxy-2',3'-didehydroinosine
Synonyms:
  • 9-[(2r,5s)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-3h-purin-6-one
  • 2',3'-DIDEHYDRO-2',3'-DIDEOXYINOSINE
  • 2',3'-Dideoxy-2',3'-didehydroinosine
  • 2'',3''-DIDEOXY-2'',3''-DIDEHYDRO- INOSINE [D4I]
  • 2'',3''-DIDEOXY-2'',3''-DIDEHYDRO- INOSINE SODIUM [D4I SODIUM]
  • 9-[(2R,5S)-5-methylol-2,5-dihydrofuran-2-yl]-3H-purin-6-one
  • 9-((2R,5S)-5-(HydroxyMethyl)-2,5-dihydrofuran-2-yl)-3H-purin-6(9H)-one
  • 9-((2R,5S)-5-(HydroxyMethyl)-2,5-dihydrofuran-2-yl)-3H-purin-6(9H)-one sodium
CAS:
42867-68-5
MF:
C10H10N4O3
MW:
234.21
EINECS:
1308068-626-2
Product Categories:
  • Nucleosides-Dideoxy Nucleosides
Mol File:
42867-68-5.mol
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2',3'-Dideoxy-2',3'-didehydroinosine Chemical Properties

Boiling point:
666.3±55.0 °C(Predicted)
Density 
1.74±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
8.92±0.70(Predicted)
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2',3'-Dideoxy-2',3'-didehydroinosine Usage And Synthesis

Uses

2’,3’-Didehydrodidanosine (Didanosine EP Impurity F) is an impurity of Didanosine (D440950), which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2).

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