(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate Chemical Properties

Boiling point:

459.6±45.0 °C(Predicted)

Density 

1.16

storage temp. 

2-8°C

pka

-4.97±0.60(Predicted)

CAS DataBase Reference

201856-57-7(CAS DataBase Reference)

(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate Usage And Synthesis

Uses

(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.

(3R,4S)-tert-Butyl 3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate(201856-57-7)Related Product Information

• Butyl acetate
• RESMETHRIN
• Ethoxyethyne
• tert-Butylchlorodiphenylsilane
• 2-Ethoxyethanol
• Ethyl vinyl ether
• Buprofezin
• DIETHOXYMETHANE
• Diethylene glycol monobutyl ether
• PHENYL VALERATE
• BUTYL OLEATE
• Ethoxyquin
• Cyhalofop-butyl
• Dibutyl phthalate
• Docetaxel
• Docetaxel
• PHENYL RESIN
• Docetaxel Metabolite M4